Category Archives: Student posts
This is my third knitted zika virus ball. This time it has the neutralizing antibodies on it. I hope to make two more, one orange without the antibodies on it and another with blue antibodies on it.
This is my second finished Zika virus yarn ball. ‘Finished’ because I have been working on the all white one I spoke of in my last post, but I haven’t figured out how to attach the neutralizing antibodies quite yet. … Continue reading
My name is Makenna Browne, I am a senior Biochemistry, Molecular Biology major, and I have decided to focus my protein portrait on Flavivirus causing Yellow Fever. I have a family history of artistic ability, but didn’t start experimenting till … Continue reading
Although they are a fun way of representing a virus capsule, iscosahedral tea cozies are a challenge to make! I started by constructing a paper mock-up around my teapot, identifying which corners needed cutting so there would be gaps for … Continue reading
This is the first of hopefully many (3-5?) knitted Zika virus balls that I’m planning on making. For the next one I’m thinking of making the base ball a solid white and adding bright blue spikes to the outside to … Continue reading
This image (which I reproduce here under fair use guidance) appears in this mornings New York Times in the article “The Global Coronavirus Crisis in Poised to Get Much, Much Worse”. The artist, Nicholas Konrad, really drives in the point!
The orange slices are the Spike proteins. The toast represents antibody molecules that have bound to the surface of the virus, creating immunoresistance for the host. This, after all, is where our hopes lie: Gaining immunity and making the virus … Continue reading
Hemocyanin PDB ID: 1NOL Blue Blood? That a Hemo-SIGN-anin that you have Hemocyanin in your blood! Hemocyanin is a protein that is found in molluscs, such as snails, octopi, and crabs, and it carries oxygen just as hemoglobin does in … Continue reading
Here are some photos from the development of the Hemagglutinin model
1918 Influenza Hemagglutinin PDB ID: 1RUZ Raha Kannan Hemagglutinin, a trimeric transmembrane protein found on viral membranes, helps viruses enter and release their viral RNA into cells. The outer portion of the protein targets sialic acid chains (present on … Continue reading
Here’s my final sculpture of antifreeze proteins and the description that went with them: PDB ID: 1EWW, 2PY2 Ally Kershner Antifreeze proteins are found in many plants and animals that live in polar habitats. They prevent freezing by binding to … Continue reading
Human Ceruloplasmin PDB ID: 4ENZ Karissa Renyer Ceruloplasmin is the main copper-carrying protein in the blood. However, it also is a ‘moonlighting’ protein, performing various other functions outside of its typical role with copper. For example, it also acts as … Continue reading
Couldn’t get a molded plastic form to have enough freedom to move so I went with wood, metal, and plastic. I also modified a mechanical cart to help it walk.
I was able to use a blue patina today on my ceruloplasmin protein pendant. Here is a before and after picture showing the transformation brought forth from the patina! I ended up sanding off the patina on the raised copper … Continue reading
Thanks to all who pitched in with some important 10th week committee work: Show tables committee. We have tables! Our show ballot committee. Clever categories! Our show poster committee. Splendid artistic view of a Nobel prize winning ion channel structure discovered by Rod MacKinnon . The artist … Continue reading
This weekend I build the wireframe for my protein project (see left). It looks much better in person than in the picture, but still needs some added volume around the wires to give it more form. I plan to do … Continue reading
Raha is just back from visiting the Art of Brick exhibition at OMSI (in Portland). Check it out!
The widely used pymol is available here. Highly recommended for adjusting your view as you work on your protein portraits projects.
The Protein: Hemagglutinin (HA), a protein involved in the viral infection process. Specifically, HA helps cells internalize the virus and eventually the viral RNA. Structure: Hemagglutinin is a trimeric transmembrane protein that extends from the surface of viruses. There are two types of … Continue reading
Wilson’s disease is a rare disorder in which too much copper accumulates in your liver, brain or organs in general. The liver is not able to filter out copper properly. I would focus Wilson copper ATPase, also known as the … Continue reading
Chris Petersen will host a tour of the collection on Tuesday of Week 8 (May 23) at 10 am. We’ll meet at the library 5th floor (Special Collections). Read about Pauling’s discovery of the alpha helix here.
This was news a few months ago but the Weihong Qiu lab in the Physics/Biophysics lab observed and reported that kinesin can walk backwards. It was previously thought that kinesin could only walk forward, in fact the Hoogenraad Lab video … Continue reading
Let me introduce Erythrocruorin, giant hemoglobin made from earthworms. This hemoglobin is HUGE, it is comprised of 144 globin chains and its skeleton is comprised of 12 globin chains. Each of these chains can carry oxygen and with its 3-fold … Continue reading
TMV is the first virus to be discovered and is found to be mostly made of protein. It is supposed to be very stable and can survive for years within a cigar or cigarette. TMV’s helical shape kind of reminds … Continue reading
Actinomycin, discovered in Streptomyces antibioticus in 1940, is the first natural antibiotic that has anti-cancer activity. Unfortunately, actinomycin does not specifically kill cancer cells, so it too toxic for general use. This molecule works by intercalating into the DNA double … Continue reading
Proteasomes break down other proteins. They help keep the cell free of damaged proteins as well as allowing the cell to recycle parts of proteins that it no longer uses. In this image, the yellow and red core is where … Continue reading
This is the P-Glycoprotein found in many cells of the human body. It’s role is to search for toxic molecules and eject them from the cell to be disposed. Using ATP, the P-Glycoprotein targets mostly hydrophobic toxic molecules in its … Continue reading
Sodium-potassium pumps create and maintain electrochemical gradients, pumping potassium ions into the cell and sodium ions out of the cell. The established gradient is a crucial part of sending electrical nerve signals and regulating the osmotic pressure in cells. When the … Continue reading
Aquaporin creates a channel for water molecules to pass through a membrane, so this molecules pops up when talking about osmosis. Aquaporin can be found in many organisms, from bacteria to eukaryotes and is made up of 4 identical chains. The molecule … Continue reading
This week please post a protein example from the Molecule of the Month and include an idea of how the dynamics of that protein could be conveyed artistically! Here’s a quick rundown of the artwork we looked at on Tuesday … Continue reading
Hi all, I wanted to say thanks for a great semester, and wanted to share this cool game I found! Foldit is a protein folding game was developed by the University of Washington. As more people play the game, researchers at … Continue reading
Below is the link for art captions. Please ensure your caption and PDB picture stay on one page. Once you are done, remember to put your project and name in the ballot on the last page. https://docs.google.com/document/d/1mApN-EBO76QV3N_XFD6QjF_qgeStUoz_0j-K3cLXpnU/edit?usp=sharing
Here are some interesting possibilities for my protein (keratin) portrait. I’m thinking about using wool as a medium, since wool is a type of keratin. Tomorrow in class I’d love to share my goals for the project and brainstorm with … Continue reading
So, if you guys were to read a comic at a presentation, how much context/background story would you feel comfortable with before getting bored? I presently have about 10 panels.