Sculpture Caption Card

Newcastle Disease Virus F-Protein in the Post-Fusion Conformation

PDB ID#: 3MAW

Exotic Newcastle virus (ENV) is a lethal and contagious antisense ssRNA viral disease of all birds, and an international threat to the agricultural poultry industry. Since this virus is only known to infect birds the bones are based on a chicken (Gallus gallus) skeleton, as are the feet. The F-protein is a trimeric surface glycofusion protein used by viruses in the Paramyxoareviridae family to fuse with host membranes. The F-protein changes from a pre- to a post-fusion structure upon binding.

Media: firm super sculpey, foil, acrylic paint, and wire.

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