Dear members of the CQLS Community,

I wanted to reach out and give you an update on the status of the Center.  It has been, as they say, an interesting year.  We have seen an easing of COVID restrictions, and with that return of staff to the Center.  We have had several personnel changes: Bo (Finance Manager), Dana (Bioinformatics Analyst), Matt (Bioinformatics Analyst), and Lynn (Admin. Assistant) have left for new opportunities.  Max Schmidt (Computational Scientist) and Steven Carrell (Bioinformatics Scientist) have joined the Center.  Konnie Handschuch has been serving as our part time Admin Assistant.

There have been changes within our laboratory space as well.  With closing of the previous Director’s lab, we’ve began the process of expanding our core laboratory into that space. A consultant has reviewed laboratory workflows for spatial optimization, and we are excited that this effort will help streamline sample processing and provide better staff space.

As part of functional realignment efforts in the Research Office, we have transferred several administrative duties to them.  Parts of CQLS billing, ordering, and HR efforts now take place in the Research Office.  This change will provide substantial capacity and personnel overlap and minimize bottlenecks.

The biocomputing side of CQLS has continued its efforts to replace and upgrade our computational infrastructure.  That has required us to retire some systems and move researchers on to newer (and improved!) components.  We have also engaged with University Information and Technology (UIT) to aggressively maintain the security posture of our systems.

Chris Sullivan has recently accepted an exciting position within the College of Earth, Oceans and Atmospheric Sciences (CEOAS) but, for the next two months, will work half time with the CQLS to enable a smooth transition. The CQLS will hire an Acting Assistant Director for Biocomputing, and we anticipate a search for a permanent position.

CQLS Bioinformatics and Data Science group continues to teach CQLS workshops and offer research consulting services.  The CQLS trainers teach introductory level workshops for learning high performance computing and Python programming, and bioinformatics workshops to learn analysis of RNAseq, genotyping, and environmental sequencing.  Bioinformatics research consulting analyzes weekly samples for COVID wastewater testing as well as many custom bioinformatics projects across the University.  The newly formed Oregon Data Science Collaborative (ODSC), in conjunction with UO and PSU, brings data science research into the CQLS.  The ODSC teaches workshops and offers research consulting on data analytics, data integration, and machine learning.  The ODSC just hosted its first state-wide data science symposium.

The coming year we will undertake several processes that will help shape the future of the CQLS. First, we will reengage with our stakeholders and steering committees, revisiting the components of the strategic plan.  Secondly, we will undertake a budget analysis in cooperation with the OSU Research Office.  This will help ensure the continued success of the Center.  Third, our Core Laboratory will work with the RO and help them construct CQLS-centered components for the new Research Equipment Laboratory Management System (RELMS).  This will, in turn, help CQLS better serve its customers.

When I accepted the position of Interim Director, I knew that there were challenges that needed to be addressed. Some involved our emergence from the restrictions imposed by the pandemic.  Others were more structural.  One thing that was certain, however, was that the Research Office is very committed to the success of CQLS.  They have been unwavering in their support and continue to help us navigate these challenging times.  CQLS will continue to be here, to provide support, guidance, and a place to grow your research.

Looking forward to this year,

Kathy

Kathryn A. Higley, Ph.D., CHP, HPS Fellow
Interim Director CQLS – Center for Quantitative Life Sciences,
Professor, School of Nuclear Science and Engineering

Christopher Sullivan at CQLS

Dear CQLS Community,

Chris Sullivan, the CQLS Assistant Director of Biocomputing, has accepted a new position within OSU’s College of Earth Ocean and Atmospheric Sciences.  While we are sad to see him leave, his new position provides exciting new opportunities for him, and continues a long relationship he has had with the computing activities of CEOAS.  Please join us in congratulating Chris in his new position within OSU. 

Chris has been an integral part of CQLS (originally CGRB) since 1999.  Under his guidance the high-performance computing resources in the CQLS have grown from a few computing servers to greater than 7000 processors with more than 7 petabytes of storage and serving more than 20 departments across the University.  Chris has had great success developing bleeding edge computing research for the CQLS and the University.  He has also been phenomenal in his success at obtaining equipment grants from the likes of IBM and OpenPOWER.

Chris will remain with the CQLS at half time for the next three months to enable a smooth transition. He remains committed to the ongoing success of CQLS and to OSU. To ensure there are no interruptions in service the CQLS will fill an interim position to manage this transition before launching a full Assistant Director search in the New Year.

Again, please join us in congratulating Chris.  We will miss him, but we know that he’s just across campus.

Sincerely, Kathryn A. Higley, Ph.D., CHP, HPS Fellow
Interim Director CQLS – Center for Quantitative Life Sciences,
Professor, School of Nuclear Science and Engineering

December 1, 2021

Colleagues,

It is my pleasure to announce that Dr. Kathryn A. Higley has been selected to serve as the Interim Director of the Center for Quantitative Life Sciences (CQLS) effective December 1.

Dr. Higley has been at OSU for 27 years, and most recently served as the Associate Director for the TRACE-OSU effort. She has a long record of both administrative and academic experience at OSU. She is a Professor and former Head of the School of Nuclear Science and Engineering in the College of Engineering at Oregon State University. She has managed OSU’s Radiation Health Physics program, including developing its online graduate degree into the largest in the country. Dr. Higley has been at Oregon State University since 1994 teaching undergraduate and graduate classes on radioecology, radiation biology, and more. She is a Council Member of the National Council on Radiation Protection and Measurements, a board member and fellow of the Health Physics Society, and a Certified Health Physicist. Dr. Higley and her students have done research in radiologically contaminated environments around the globe.

I am excited to start working with Dr. Higley, CQLS staff and affiliated faculty to take the center to the next stage. Please join me in welcoming her to the CQLS and RO community!

Sincerely, Irem Y. Tumer, Ph.D., ASME Fellow
Vice President for Research

Oregon State University (OSU), in Corvallis and founded in 1868, is Oregon’s largest university. As a public land-grant university, conducting scientific research is part of OSU’s mission. However, the school’s new information and technology officer found it unacceptable that the university could not engage in health care research requiring HIPAA-level security standards because its previous cloud service didn’t meet security requirements. To address this challenge, the school chose to migrate its data to Microsoft Azure. As a result, the university now has reliable, compliant, and more secure data management that has positioned the school for additional research opportunities.

Read the full article on Microsoft’s website.

2021-22 CQLS Seminar Series Schedule

Fall Term 2021
September 29, 2021Chris Plaisier
Arizona State University
Finding new therapies for mesothelioma
October 13, 2021TRACE
Oregon State University
TRACE COVID Community Surveillance Project
October 27, 2021David Garcia
University of Oregon
Prion-based forms of RNA-modifying enzymes
November 10, 2021Ya-chieh Hsu
Harvard University
Deep: Stem Cells at the Nexus of the Niche, Physiology, and the External Environment
Winter Term 2022
January 5, 2022TBD
January 19, 2022Carrie Hanna
Oregon Health and Science University
Using genome editing technology to create biomedical models in the nonhuman primate
February 2, 2022Jennifer Nemhauser
University of Washington
Babbage’s Cabbage: The Logic of Information Processing In Plants
February 16, 2022Yanming Di
Oregon State University
What is a replicate?
March 2, 2022Dr. Shobhan Gaddameedhi
North Carolina State University
Environmental Regulation of Genomic Stability and Human Health through the Circadian Clock
Spring Term 2022
March 30, 2022Mike Harms
University of Oregon
Ensembles, epistasis, and evolution: how biophysics shapes evolutionary outcomes
April 13, 2022Andrew Gentles
Stanford University
Atlas of Clinically Distinct Cell States and Cellular Ecosystems Across Human Solid Tumors
April 27, 2022CANCELLED – Yehenew Agazie
West Virginia University
TBD
May 18, 2022 (rescheduled for Fall2022)Elias Fernandez
University of Tennessee
TBD
June 1, 2022 (rescheduled for Fall2022)Sourav Ghosh
Yale School of Medicine
TBD

Online

In celebration of our recent name change, the theme for this year is “Frontiers at the Intersection of the Life & Quantitative Sciences.” Anyone with an interest in life sciences or quantitative sciences is invited to attend. The Fall Conference will feature excellent science presentations from invited guest speakers, OSU faculty, students and staff. 

Because this is our first conference since our name change (and because the event is fully online this year) the conference this year is completely free for all attendees.

The poster session will be held online on Friday, September 17. More details of the format and time will be provided soon. Posters are welcome from all participants. Posters from registered undergraduate students, graduate students and postdoctoral fellows/trainees will be eligible for one of three cash awards, and there will be one award for lighting talks. 

DEADLINES
  • Lightning Talk Registration: September 10
  • Poster Registration: September 15
  • Conference Registration: September 15
Thank you to our 2021 Fall Conference Committee

Kevin Brown, Pharmaceutical Sciences and Chemical, Biological, & Environmental Engineering
Molly Burke, Integrative Biology
Maude David, Microbiology & Pharmaceutical Sciences
Patrick De Leenheer, Mathematics and Integrative Biology
Perry Hystad, Public Health & Human Science
Natalia Shulzhenko, Biomedical Sciences, Carlson College of Veterinary Medicine

Frontiers at the Intersection of the Life and Quantitative Sciences

Friday, September 17, 2021 Online

LocationTimeEvent
Conference Floor8:00Doors open. Explore the virtual conference space and watch a SpatialChat tutorial
Stage9:00Brett Tyler, Director, CQLSIntroduction to the Center for Quantitative Life Sciences
Stage9:30Matthew Bennett, Professor of Biosciences, Rice UniversityDynamics of synthetic gene circuits: from cells to consortia to organisms
Free10:15Break (setup for posters)
Stage10:45Gail Rosen, Professor, Electrical and Computer Engineering, Drexel UniversityMachine Learning of Microbiomes: Learning and Exploring Structure and Function of DNA and Proteins at Multiple Scales
Stage11:30Richard Rodrigues, Bioinformatician at Leidos Biomedical Research, IncHost-Microbiome Multi-Omics Data Integration in Cancer Immunotherapy
Discussion Rooms12:00Lunch (networking with guest speakers and Presentation by Agilent from 12:15-12:45)
Stage1:00Maya KaelbererMedical Instructor in the Department of Medicine, Duke UniversitySugar transduction in the gut
Stage1:45Marian Hettiaratchi, Assistant Professor, University of OregonDeveloping Biomaterials for Tissue Repair using Bio-transport Modeling
Stage2:15Mark Phillips, Department of Integrative Biology, Oregon State UniversityUsing Experimental Evolution to Study the Genetics of Adaptation
Free2:45Break
Stage3:00Lightning Talks (you can vote for your favorite lightning talk at shell.cqls.oregonstate.edu/voting)
Poster Rooms3:45Poster Session (you can vote for your favorite poster session at shell.cqls.oregonstate.edu/voting)
Stage4:45Closing Remarks

THANK YOU TO OUR 2021 FALL CONFERENCE COMMITTEE:

Kevin Brown, Pharmaceutical Sciences and Chemical, Biological, & Environmental Engineering
Molly Burke, Integrative Biology
Maude David, Microbiology & Pharmaceutical Sciences
Patrick De Leenheer, Mathematics and Integrative Biology
Perry Hystad, Public Health & Human Science
Natalia Shulzhenko, Biomedical Sciences, Carlson College of Veterinary Medicine

THANK YOU TO OUR 2021 FALL CONFERENCE COMMITTEE: