Brent Kronmiller, Edward Davis, David Hendrix, Thomas Sharpton, Clinton Epps, Pankaj Jaiswal, Stephen Ramsey et al – Pan-tissue transcriptome analysis of long noncoding RNAs in the American beaver Castor canadensis

Friday, September 20, 2019 CH2M HILL Alumni Center

Congratulations to our winners! To all the participants and presenters, another thank you for your contributions. We look forward to welcoming the CGRB Community to the 2020 Spring Conference on April 24, 2020.

Undergraduate Poster: Kelsey Shimoda “Altering metabolic gene expression in fruit flies: effects on longevity and brain aging”
Graduate Poster:             Benjamin Americus “Elegant Infection Machines: Nematocyst diversification within Myxozoa”
                                           Daniel Schneck “Phenotypic and transcriptional responses to different light regimes in allopatric populations of Tigriopus californicus”
                                            Manoj Gurung “Lactobacilli ameliorate western diet induced diabetes by preventing hepatic mitochondrial damage”
                                            Miranda Leek “A Biochemical and Biophysical Investigation into the Pathological Gain-of-Function of Nitrated Hsp90”
                                            Rebecca Veitch “Exposure to Light at Night Alters DNA Methylation and Expression of Proliferative and DNA Damage Repair Genes”
Post-Doc Poster :               Allie Graham “Independent losses of the Hypoxia-Inducible Factor (HIF) Pathway within Crustacea”
Lightning Talks:                 Eileen Chow “Daily blue light exposure accelerates aging in Drosophila melanogaster”

Raffle drawing for voting in all categories:             1st place – Miranda Leek
                                                                                       2nd place – Alexandre Sathler

8:00Registration & refreshments (Poster & sponsor setup) 
8:50Brett Tyler, Director, CGRB
Introduction, CGRB update
9:15Andrew Annalora, Environmental and Molecular Toxicology
Exploring Splice Variant Biology in Nuclear Receptor and Cytochrome P450 Genes
9:40Ed Kelly, University of Washington
Tissue Chips for Human Disease Modeling
10:20Break
10:50Lightning Talks Moderated by Jeff Anderson
Featuring: Martin Pearce, Stephanie Bollmann, Benjamin Americus, Evan Carpenter, Eileen Chow, Lauren Chan, Nolan Newman, Alexandra Weisberg
11:35Felipe Barreto, Integrative Biology
Genomics in the Tidepool: Functional and Population Genetics of Adaptation and Speciation in a Tiny Crustacean
12:00Kevin Brown, Pharmaceutical Sciences and Chemical, Biological, and Environmental Engineering
Adventures in Complex Systems
12:25Lunch
1:25Afua Nyarko, Biochemistry & Biophysics
Selectivity and Specificity in Cancer Regulatory Proteins
1:50Daniel Liefwalker, Oregon Health and Science University 
Therapeutic strategies targeting c-MYC
2:30Lightning Talks
Moderated by Jeff Anderson
Featuring: Armando Alcazar Magana, Christine Tataru, Sarah Alto, Anh Ha, Heather Forsythe, Kayla Jara, Rebecca France, Rachel Franklin
3:15Break
3:45Morgan Giers, Chemical, Biological, and Environmental Engineering
Regenerating the Intervertebral Disc: Developing Effective Therapies in a Nutrient Limited Environment  
4:10Doris Taylor, Texas Heart Institute
Building Solutions for Heart Disease: A 2019 Update
5:00-7:30Poster Session Reception, Sponsor Displays

THANK YOU TO OUR 2019 FALL CONFERENCE COMMITTEE:

Jaga Giebultowicz, Department of Integrative Biology
Craig Marcus, Environmental and Molecular Toxicology
Jeff Anderson, Department of Botany and Plant Pathology
Viviana Perez, Department of Biochemistry and Biophysics

Fall Term 2019
October 9, 2019Marilyn Roossinck
The Pennsylvania State University
Lessons in Virus Ecology from Forty Years of Research
Host: Jerri Bartholomew
October 23, 2019Ran Blekhman
The University of Minnesota
Population and Functional Genomics of Host-Microbiome Interactions
Host: Tom Sharpton
November 6, 2019Mark Farman
UC Davis
Telomeric transposons: major drivers of fungal genome evolution and guards against genome change
Host: Michael Freitag
December 4, 2019Carolina Tropini
The University of British Columbia
Physical perturbations to the gut microbiota during health and disease
Host: Natalia Shulzhenko
Winter Term 2020
January 8, 2020Chris Hittinger
University of Wisconsin-Madison
Host: Joey Spatafora
Genomic and metabolic evolution across budding yeasts
January 22, 2020Audrey Gasch
University of Wisconsin-Madison
Host: Michael Freitag
The genetic basis of aneuploidy tolerance in wild yeast
February 19, 2020Jill Banfield
UC Berkeley
Host: Steve Giovannoni
March 4, 2020Josh Cuperus
University of Washington
Host: Molly Megraw, John Fowler
Spring Term 2020
April 1, 2020Pankaj Kapahi
USC Leonard Davis
Host: Jaga Giebultowicz
April 15, 2020Jose Dinneny
Stanford University
Host: John Fowler
May 13, 2020TBD
May 27, 2020TBD

Friday, October 12, 2018


Poster Award Winners

Undergraduate student: Michaela Buchanan, Computer Sci/Biochemistry & Biophysics  Using GPUs to Classify Oceans of Data
Graduate student:  Courtney Armour, MCB  A Metagenomic Meta-Analysis Reveals Functional Signatures of Health and Disease in the Human Gut Microbiome
Postdoc/Trainer: T. William O’Neill, Biomedical Sciences  Creating 3-Dimensional Models from Serial Histologic Sections Using Open-Source Software

8:00Registration & refreshments (Poster & sponsor setup) 
9:00Brett Tyler, Director, CGRB
Introduction
9:30Helen Poynton, University of Massachusetts   
The Toxicogenome of Hyalella Azteca, building genomic resources for healthy ecosystems
10:20Break (Poster & sponsor setup / displays)
10:45Gerrad Jones, Biological & Ecological Engineering
Environmental Change Drives Global Soil Element Fluxes
11:15James Watson, College of Earth, Ocean & Atmospheric Science
Manifold Learning of Multi-scale Dynamics in Complex Systems
11:45Joe Christison, Office of Commercialization & Corporate Development
Patenting and Commercializing University Discoveries
12:10Lunch (Poster and Sponsor setups / displays)
1:15Daniel Coleman, OHSU
Targeting BET Bromodomain Proteins in Castration-Resistant Prostate Cancer
2:10Maria Franco, Biochemistry & Biophysics
Role of Redox Signaling in Tumor Metabolic Reprogramming
2:40James Strother, Integrative Biology
Elucidation of neural circuit structures through imaging, optogenetics, and behavior
3:05Break 
3:30Maude David, Depts of Microbiology & Pharmacy
Children with autism and their typically-developing siblings differ in exact sequence variants and predicted functions of stool-associated microbes
4:00Vladimir Shulaev, University of North Texas
Neuroprotective effect of 17β-Estradiol (E2) on rat brain
4:50Closing remarks
5:00 – 7:30Poster Session/Reception, Sponsor Displays

Thank you to our conference committee:

Jared LeBoldus, Assistant Professor, Botany & Plant Pathology
Claudia Maier, Professor, Chemistry
Natalia Shulzhenko, Assistant Professor, Vet Biomedical Science

Fall Term 2018
September 26, 2018Andrew Cato
Karlsruhe Institutue of Technology, Germany
Development of Bag-1L as a Therapeutic Target in Androgen Receptor-Dependent Prostate Cancer
Host: Siva Kolluri
October 10, 2018Samara Reck-Peterson
UC San Diego
Molecular mechanisms of microtubule-based motors: how teams of motors work
Host: Michael Freitag
October 24, 2018Siobhan Brady
UC Davis
From networks to switches: systems approaches to unravel the control of biological processes necessary for plant life
Host: John Fowler/Molly Megraw
November 7, 2018Fitnat Yildiz
UC Santa Clara
Mechanisms and regulation of biofilm formation in Vibrio cholerae
Host: Claudia Hase
Winter Term 2019
Feruary 8, 2019William Hersh
OHSU
Three amazing ideas about microbial biogeography that will blow your mind
Host: Denise Hynes
March 6, 2019Nadja Cech
University of North Carolina – Greensboro
Anti-Virulence Strategies Against Drug Resistant Superbugs
Host: Sandra Loesgen
Spring Term 2019
April 3, 2019Chris Marx
University of Idaho
Phenotypic heterogeneity between genetically identical cells permits growth with letal levels of formaldehyde stress
Host: Patrick de Leenheer
April 17,. 2019Melissa Haendel
OHSU/OSU
The Yellow Brick Road of Open Science: Barriers to bringing data to its highest valued use
Host: Brett Tyler
May 1, 2019Kristine Alpi
OHSU
Host: Melissa Haendel
May 15, 2019Lucia Carbone
OHSU
Host: Tom Sharpton
May 29, 2019Andrew Kern
University of Oregon
Putting the HAL in Haldane: leveraging supervised machine learning for population genetics
Host: Aaron Liston

Friday, April 27, 2018

Conference Award Winners

Lightning Talk: Ellie Bors, Population genomics of rapid range expansion during marine invasions
Poster: Lilian Padgitt-Cobb, Toward a phased, diploid assembly of the hop genome

Program

8:00 – 9:00Registration & refreshments (Poster & lightning talk slides setup) 
9:00 – 9:10Chris Sullivan, Assistant Director for Biocomputing, CGRB
Opening Remarks
  Moderator: Duo Jiang, Assistant Professor, Statistics
9:10 – 10:00Haiyan Huang, UC Berkeley
Inferring Gene Interactions and Functional Modules Beyond Standard Statistical Models
10:00 – 10:25Break,time for poster setup
10:25 – 10:50David Hendrix, Assistant Professor, Biochemistry & Biophysics, EECS
Large-scale Automated Annotation and Analysis of RNA Secondary Structure
10:50 – 12:15Lightning talks
Moderator: Molly Megraw, Assistant Professor, Botany & Plant Pathology
12:15 – 1:20Lunch and Poster Session (Poster & Lightning Talk slides judged)
Poster & lightning talk ballot envelopes will be picked up for counting right after lunch
  Moderator: Rebecca Hutchinson, Assistant Professor, Fisheries & Wildlife, EECS
1:20 – 1:45Susan Tilton, Assistant Professor, Environmental & Molecular Toxicology
A 3D Vitro Respiratory Model for Predicting Chemical Toxicity
1:45 – 2:10Stephen Ramsey, Assistant Professor, Biomedical Sciences, EECS
Machine-Learning for Identifying Functional Noncoding SNPs
2:10 – 2:35Clinton Epps, Associate Professor, Fisheries & Wildlife, CAS  
Genetic applications in the Conservation and Management of Bighorn Sheep
2:35 – 3:00Break
3:00 – 3:50Fei Fang, Carnegie Mellon
Machine Learning and Game Theory for Biodiversity Conservation
3:50 – 4:00Vrushali Bokil, Associate Professor, Mathematics
Awards and Closing Remarks

Thank you to our conference committee:

Vrushali Bokil – Associate Professor, Mathematics
Rebecca Hutchinson – Assistant Professor, EECS, Fisheries & Wildlife
Duo Jiang – Assistant Professor, Statistics
Molly Megraw – Assistant Professor, Botany & Plant Pathology

Friday, September 8, 2017

Poster Award Winners

 Postdoc/Trainee: Fadi El-Rami, Subcellular proteomics of the 2016 WHO Neisseria gonorrhoeae reference strains for identification of vaccine candidates and antibiotic resistance signatures
 Grad student: Aayushi Manchanda, Loss of otoferlin alters the transcriptome profile and ribbon synapse architecture of sensory hair cells
 Undergrad student: Ryan Kitchen, CASSA: The new fast GPU DNA Sequence Aligner

Program

8:00Registration & refreshments (Poster & sponsor setup) 
9:00Brett Tyler, Director, CGRB
Introduction, CGRB update
  Moderator: Aleksandra Sikora, Pharmaceutical Sciences
9:25Caroline Attardo Genco, Tufts University 
Sex as a variable: Distinct Neisseria gonorrhoeae gene expression signatures expressed during mucosal infection in men and women
10:10Break (Poster & sponsor setup / displays)
10:30Nathan Campbell,  Columbia River Inter-Tribal Fish Commission 
Genotyping in Thousands by sequencing: A low cost, high-throughput, targeted SNP genotyping method
11:15Olena Taratula, College of Pharmacy  
A Tumor-Activatable Theranostic Nanomedicine Platform for NIR Fluorescence-Guided Surgery and Phototherapy
11:40Posy Busby, Botany & Plant Pathology 
Host genetic structuring of leaf endophyte communities in Populus and Maize
12:05Lunch (Poster and Sponsor setups / displays)
  Moderator: Brent Kronmiller, CGRB
1:20Melissa Haendel, OHSU
Crossing the chasm of semantic despair: ontologies to unify genomics and phenomics
2:05Brett Tyler, Botany & Plant Pathology
Does the pathogen always win – the co-evolutionary struggle between soybean and its oomycete pathogen Phytophthora sojae
2:30Molly Burke, Integrative Biology
Genomic lessons from laboratory evolution experiments  
2:55Break 
3:15Marian Waterman, UC Irvine 
WNT signaling and tumor heterogeneity                     
4:00Maria Clara Franco, Biochemistry & Biophysics
The Two Faces of Nitrated Proteins: Neurodegeneration and Cancer
4:25David Myrold, Crop & Soil Science
Glimpses into the microbial communities of Oregon soils
4:50Janine Trempy, Associate Vice Provost for Academic Affairs
Closing remarks
5:00 – 7:30Poster Session/Reception, Sponsor Displays

Thank you to our conference committee:

Pankaj Jaiswal, Botany & Plant Pathology
Ryan Mehl, Biochemistry & Biophysics
Aleksandra Sikora, Pharmaceutical Sciences

Fall Term 2017
September 27, 2017Geoffrey Wahl
The Salk Institute
Understanding Intra-tumoral heterogeneity using a developmental lens
Host: Arup Indra
October 11, 2017David Thomas
Biochemistry, Molecular Biology and Biophysics
University of Minnesota
Muscle Protein Structural Dynamics and Therapeutic Discovery 
Host: Weihong Qiu
October 25, 2017
Cosponsored by the Departments of Microbiology and Chemistry

ROOM CHANGE
**Withycombe 109**
Paul Jensen
Center for Marine Biotechnology & Biomedicine
UC San Diego
Ecological and evolutionary perspectives on secondary metabolism in marine actinobacteria
Host: Sandra Loesgen
November 8, 2017Brenna Henn
Stony Brook University
What do we gain by studying African genomes? : Examples from human evolution
Host: Thomas Sharpton 
December 6, 2017
Pat Schloss
University of Michigan
Understanding Disease through the Lens of the Microbiome
Host: Thomas Sharpton 
Winter Term 2018
February 7, 2018Scott Landfear
Dept of Molecular Microbiology & Immunology
OHSU
Critical Roles for Glucose Transporters in Parasitic Protozoa: From Cell Biology to Drug Discovery
Host: Sandra Loesgen
February 21, 2018Jason Slot
Fungal Evolutionary Genomics
The Ohio State University
Investigating fungal chemical ecology with evolutionary genomics
Host: Michael Freitag
March 7, 2018Rosalie Sears
Molecular and Medical Genetics
OHSU
Modeling and targeting intra-tumor phenotypic heterogeneity and cellular plasticity
Host: Siva Kolluri
Spring Term 2018
April 4, 2018John Taylor
UC Berkeley
The species problem for fungi in the era of genomics
Host: Nik Grünwald
April 18, 2018Catherine Royer
Biological Sciences
Rensselaer Polytechnic Institute
Pressure-based mapping of protein conformational landscapes
Host: Elisar Barbar
May 2, 2018Maret Traber
Linus Pauling Institute
Oregon State University
Ferroptosis, Mechanism of Cell Death in Vitamin E Deficiency During Embryogenesis?
May 16, 2018Steve Reichow
Chemistry
Portland State  University
Native Lens Gap Junctions Visualized at Near-Atomic Resolution by CryoEM
Host: Elisar Barbar
May 29, 2018
NOTE: Date change
Tuesday, May 29   3:30-4:30    ALS 4001
Rebecca Fry
Environmental Sciences and Engineering
UNC Chapel Hill 
The placental epigenome as a driver of early and later life health effects
Host: Molly Kile

Wednesday, June 21, 2017

 Program  provisional

8:00Registration & refreshments (Poster setup) 
8:30Brian Wall, Assistant Vice President, Research, Commercialization & Industry Partnerships, Oregon State University
Introduction
Session 1  Moderator: Joseph McGuire, OSU; Monique Lajeunesse, OSU
8:40Joseph Beckman, Distinguished Professor, Environmental & Molecular Toxicology, Oregon State University
Towards curing ALS (Lou Gehrig’s disease) and other neurodegenerative diseases.
9:00Laura Heiser, Assistant Professor, Biomedical Engineering, Oregon Health Science University
9:20John Bial, CEO, Yecuris
Commercial Translation, taking ideas from theory to practice
9:40Kristina Young, Earle A. Chiles Research Institute
Translational Research: Rational and Relevant Science
10:00Discussion
10:20Coffee Break 
Session 2  Moderator: Jeff Chang, OSU; Kristof Torkenczy, OHSU
10:50Hilary Ely, Life Sciences Applications R&D Engineer, HP Inc.
Advancing HP Beyond Ink: Applying HP’s technology to life sciences and healthcare
11:10Robyn Tanguay, Distinguished Professor, Environmental & Molecular Toxicology, Oregon State University
Integrating the power of the zebrafish model with automation to accelerate scientific discoveries
11:30Sandra Rugonyi, Associate Professor, Biomedical Engineering, Oregon Health Science University 
Predicting risks and outcomes in cardiovascular disease. Progress and challenges
11:50Yigit Menguc, Assitant Professor, Mechanical Engineering, Oregon State University
Soft Robotics combining Soft Materials, Mechanisms, and Manufacturing
12:10Discussion
12:30Lunch and poster session
Session 3   Moderator: Michaele Armstrong, Oregon Bioscience Association; Sigrid Noreng, OHSU
1:30Kyle Ellrott, Assistant Professor, Biomedical Engineering, Oregon Health Science University 
Big Data and Cancer Genomics
1:50Elain Fu, Assistant Professor, Bioengineering, Oregon State University
Paper-based testing for precision health
2:10Matthew Ryder, Research & Development Surface Biochemist, Qorvo
Qorvo Biosensors
2:30Summer Gibbs, Assistant Professor, Biomedical Engineering, Oregon Health Science University
2:50Discussion
3:10Coffee Break 
Session 4Moderator: Summer Gibbs, OHSU; Ward Shalash, OSU
3:40Karl Schilke, Assistant Professor, Bioengineering, Oregon State University
Bionanoparticles: A versatile platform technology for personalized medicine and bioprocessing
4:00Brian Maloney, Chemical Engineer, Patheon
Patheon Oregon Site Overview
4:20Greg Herman, Professor, Chemical Engineering, Oregon State University
See Through Sensors
4:40Discussion
5:00Brett Tyler, Director, Center for Genome Research & Biocomputing, Oregon State University
Closing 
5:10 – 7:00Poster Session and Networking Reception (cash bar)

Friday, April 7, 2017

Conference Award Winners:

Lightning Talk: Zachary Foster,  “Metacoder: An R package for visualization and manipulation of community taxonomic diversity data”
Poster: Khiem Lam,  “Exploring the Microbiome of Cervical Cancer through Transkingdom Networks”

Program

8:00Registration & refreshments (Poster & lightning talk slides setup) 
9:00Brett Tyler, Director, CGRB
  Opening Remarks
9:10Ian Muñoz, Assistant Computational Scientist, CGRB
Using Amazon Web Services (AWS) for Batch Processing
9:25Lightning talksModerator: Stephen Ramsey, Assistant Professor, Biomedical Sciences and School of Electrical Engineering & Computer Science
10:35Break (Poster setup)
11:00Brent Kronmiller, Bioinformatics Analyst, CGRB
Draft Genome of the North American Beaver (Castor canadensis)
11:25Reidun Twarock, Departments of Mathematics and Biology University of York, England
Solving a Viral Enigma: Discovery of a hidden code in RNA viral genomes provides a new perspective on viral evolution and anti-viral therapy
12:15Lunch and Poster Session (Posters & Lightning Talk slides judged) 
Poster & lightning talk ballot envelopes will be picked up for counting right after lunch
  Moderator: Duo Jiang, Assistant Professor, Statistics
1:20Katherine McLaughlin, Assistant Professor, Statistics 
Accessing Hidden Populations at High Risk for HIV/AIDS Using Respondent-Driven Sampling
1:45Afua Nyarko, Assistant Professor, Biochemistry & Biophysics
Molecular basis for regulation of the Yorkie transcription co-activator
2:10Sharmodeep Bhattacharyya, Assistant Professor, Statistics
Union-of-Intersection (UoI) methods for Data-driven Discovery and Prediction
2:35Break
3:00Molly Megraw, Assistant Professor, Botany & Plant Pathology 
Using Machine Learning Models to Determine the Principles Behind Tissue-Specific Gene Expression
3:25Benjamin Dalziel, Assistant Professor, Integrative Biology and Mathematics
Cities as natural experiments in bacterial metacommunity dynamics
3:50Awards Ceremony, Brett Tyler
4:00Reinhard Laubenbacher, Center for Quantitative Medicine, UConn Health
Iron metabolism and its role in breast cancer
4:50David Hendrix, Biochemistry & Biophysics and Electrical Engineering & Computer Science
Closing remarks