Blakemore Research Group

Target: Bryce

Total Syntheses of Proposed Structures of 4,10-Dihydroxy-8,12-guaianolides

Method: Eliseo

[Enantioselective Organocopper-Catalyzed Hetero Diels−Alder Reaction through in Situ Oxidation of Ethers into Enol Ethers]

Spotlight: Vivian

Research update

NMR Problem:

1) https://www.chem.uci.edu/~jsnowick/organicspectroscopy/2013-MT-I.3.pdf

2) https://www.chem.uci.edu/~jsnowick/organicspectroscopy/2014-MT-II.2.pdf

Target: Yang

Method: Blaik

Nontraditional Fragment Couplings of Alcohols and Carboxylic Acids: C(sp³)–C(sp³) Cross-Coupling via Radical Sorting

Spotlight: Kik

Research update

Target: Eliseo

Concise Enantioselective Total Synthesis of Daphenylline Enabled by an Intramolecular Oxidative Dearomatization

Method: Vivian

Decarboxylative Borylation and Cross-Coupling of (Hetero)aryl Acids Enabled by Copper Charge Transfer Catalysis

Spotlight: Layhna

PDF: Erik Alexanian (University of North Carolina)

Target: Blaik

A Highly Convergent Total Synthesis of Norhalichondrin B

A Reverse Approach to the Total Synthesis of Halichondrin B

Method: Kik

Copper-Catalyzed Regiodivergent and Enantioselective Hydrosilylation of Allenes

Spotlight: Bryce

[Profile name / Research update; optional — upload slides as PDF]

Target: Vivian

Total Syntheses of Scabrolide A and Nominal Scabrolide B

Method: Layhna

Rh-Catalyzed Regio- and Enantioselective Allylic Phosphinylation

Spotlight: Yang

[Profile name / Research update; optional — upload slides as PDF]

Target: Kik

Total Synthesis of (-)-Acutumine (1)

Total Synthesis of (-)-Acutumine (2)

Method: Bryce

TMSCF₂Br-Enabled Fluorination–Aminocarbonylation of Aldehydes: Modular Access to α-Fluoroamides

Spotlight: Eliseo

[Profile name / Research update; optional — upload slides as PDF]

Target: Layhna

Total Synthesis of (−)-Lamellodysidine A via an Intramolecular Diels−Alder Reaction

Method: Yang

[Link]

Spotlight: Blaik

Philipp Klahn

Target: Bryce

[Link]

Method: Eliseo

Oxyenamides as Versatile Building Blocks for a Highly Stereoselective One-Pot Synthesis of the 1,3-Diamino-2-ol-Scaffold Containing Three Continuous Stereocenters

Spotlight: Vivian

Jon Tunge

Target: Yang

Angew. Chem. Int. Ed., 2021, DOI: 10.1002/anie.202109786

Method: Blaik

[Link]

Spotlight: Kik

Profile- Prof. Janine Cossy

Target: Yang

Postponed

Method: Vivian

An Efficient Approach for 3,3-Disubstituted Oxindoles Synthesis:
Aryl Iodine Catalyzed Intramolecular C−N Bond Oxidative Cross Coupling

Spotlight: Layhna

Research update!