{"id":329,"date":"2020-04-09T17:48:45","date_gmt":"2020-04-09T17:48:45","guid":{"rendered":"http:\/\/blogs.oregonstate.edu\/vanbreemen\/?page_id=329"},"modified":"2020-04-09T23:59:47","modified_gmt":"2020-04-09T23:59:47","slug":"instruments","status":"publish","type":"page","link":"https:\/\/blogs.oregonstate.edu\/vanbreemen\/instruments\/","title":{"rendered":"Lab Instruments"},"content":{"rendered":"\n

“The philosophies of one age have become the absurdities of the next, and the foolishness of yesterday ahs beocme the wisdom of tomorrow.”<\/em><\/p>Sir William Osler (1849 – 1919)<\/cite><\/blockquote>\n\n\n\n

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Shimadzu LCMS-9030 QToF <\/strong>
This newest high-resolution mass spectrometer is equipped with a Shimadzu Nexera UHPLC system. <\/strong>It provides fast and sensitive accurate mass measurements during MS or MS\/MS operation. <\/p>\n\n\n\n

Primary use: high resolution mass measurement, structure elucidation, metabolite identification, untargeted data-dependent and data-independent acquisition for drug discovery.<\/p>\n\n\n\n

Current projects include: Superwarfarin study, Red Clover study, Estrogen study, Flavonoid study.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Shimadzu LCMS-8060 triple quadrupole<\/strong> mass spectrometer equipped with a Shimadzu Nexera UHPLC system. The LCMS-8060 is the fastest scanning and polarity switching mass spectrometer in production.<\/p>\n\n\n\n

Primary use: quantification of small molecules such as oxidized lipid biomarkers, vitamins, phytosterols, sphingolipids, natural products.<\/p>\n\n\n\n

Current Projects: Superwarfarin study, Red Clover study, Flavonoid study.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Shimadzu LCMS-8050 triple quadruple <\/strong>mass spectrometer equipped with a Shimadzu Nexera UHPLC system. Similar to the LCMS-8060, this model also provides fast scanning and polarity switching for quantitative analysis. This instrument is equipped with a high capacity Shimadzu SIL-30ACMP autosampler (324 sample rack).<\/p>\n\n\n\n

Primary use: quantification of small molecules such as oxidized lipid biomarkers, vitamins, phytosterols, sphingolipids, natural products.<\/p>\n\n\n\n

Current Projects: Flavonoid study, Cell Membrane Permeability study.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Tecan Freedom EVO 75 <\/strong>liquid handler equipped with single and multi-channel pipetting arms.<\/p>\n\n\n\n

Uses: Dilution, aliquoting, small scale reactions, affinity selection screening, all in 96 and 384 well plate format.<\/p>\n<\/div>\n<\/div>\n\n\n\n

Other Instruments<\/h3>\n\n\n\n