Publications

Google Scholar

2020

Justin Rosch, Allison DuRoss, Madeleine Landry and Conroy Sun, Formulation of Folate-Modified Raltitrexed-loaded Nanoparticles for Colorectal Cancer Theranostics. Pharmaceutics, In Press.

https://www.mdpi.com/1999-4923/12/2/133

2019

Megan Neufeld, Allison DuRoss, Madeleine Landry, Hayden Winter, Andrea Goforth, and Conroy Sun, Co-delivery of PARP and PI3K inhibitors by nanoscale metal–organic frameworks for enhanced tumor chemoradiation. Nano Research, 2019 12(12): 3003-3017

https://link.springer.com/article/10.1007/s12274-019-2544-z

Justin Rosch, Madeleine Landry, Charles R. Thomas, and Conroy Sun, Enhancing Chemoradiation of Colorectal Cancer Through Targeted Delivery of Raltitrexed by Hyaluronic Acid Coated Nanoparticles. Nanoscale, 2019 11, 13947-13960

https://pubs.rsc.org/en/content/articlepdf/2019/NR/C9NR04320A

Allison DuRoss, Megan Neufeld, Shushan Rana, Charles R. Thomas, and Conroy Sun, Integrating Nanomedicine into Clinical Radiotherapy Regimens. Advanced Drug Delivery Reviews, 2019 144, 35-56

https://doi.org/10.1016/j.addr.2019.07.002

Yufu Ren, Hayden Winter, Justin Rosch, Kyungoh Jung, Allison DuRoss, Madeleine Landry, Guillem Pratx, and Conroy Sun, PEGylated β-NaGdF4:Tb@CaF2 core/shell nanophosphors for enhanced radioluminescence and folate targeting. ACS Applied Nano Materials, 2019 2(6): 3718-3727

https://pubs.acs.org/doi/10.1021/acsanm.9b00629

Majid Badieirostami, Colin Carpenter, Guillem Pratx, Lei Xing, and Conroy Sun, Upconversion luminescence imaging of tumors with EGFR-targeted nanophosphors. MRS Advances, 2019 4(46): 2461-2470

https://doi.org/10.1557/adv.2019.242

Allison DuRoss, Megan Neufeld, Madeleine Landry, Justin Rosch, Colin Eaton, Gaurav Sahay, Charles Thomas, and Conroy Sun, Micellar Formulation of Talazoparib and Buparlisib for Enhanced DNA Damage in Breast Cancer Chemoradiotherapy. ACS Applied Materials & Interfaces, 2019 11(13): 12342-12356

https://pubs.acs.org/doi/10.1021/acsami.9b02408

Justin Rosch, Hayden Winter, Allison DuRoss, Gaurav Sahay, and Conroy Sun, Inverse-micelle synthesis of doxorubicin-loaded alginate/chitosan nanoparticles and in vitro assessment of breast cancer cytotoxicity. Colloid and Interface Science Communications, 2019 28: 69-74

https://www.sciencedirect.com/science/article/pii/S2215038218301419

Justin Klein, Conroy Sun, and Guillem Pratx, Radioluminescence in Biomedicine: Physics, Applications, and Models. Physics in Medicine and Biology, 2019 64 (4): 04TR01

http://iopscience.iop.org/article/10.1088/1361-6560/aaf4de

2018

Justin Rosch, Anna Brown, Allison DuRoss, Gaurav Sahay, and Conroy Sun, Nanoalginates via Inverse-micelle Synthesis: Doxorubicin-encapsulation and Breast Cancer Cytotoxicity. Nanoscale Research Letters, 2018 13: 350

https://nanoscalereslett.springeropen.com/articles/10.1186/s11671-018-2748-2

Dominik Naczynski, Jason Stafford, Silvan Turkan, Cesare Jenkins, Ai Leen Koh, Conroy Sun, and Lei Xing, Rare earth doped nanoparticles for short-wave infrared fluorescence bioimaging and molecular targeting of αVβ3 expressing tumors. Molecular Imaging, 2018 17: 1536012118799131

http://journals.sagepub.com/doi/full/10.1177/1536012118799131

Anna Brown, Hayden Winter, Gaurav Sahay, Andrea Goforth and Conroy Sun, Facile synthesis and of ligand-free iridium nanoparticles and their in vitro biocompatibility. Nanoscale Research Letters, 2018 13: 208

https://nanoscalereslett.springeropen.com/articles/10.1186/s11671-018-2621-3

Anna Brown, Marc Kai, Allison DuRoss, Gaurav Sahay, and Conroy Sun, Biodistribution and toxicity of micellar platinum nanoparticles in mice via intravenous administration. Nanomaterials, 2018 8(6): E410

http://www.mdpi.com/2079-4991/8/6/410

Ema Robinson, Kelvin MacDonald, Kai Slaughter, Madison McKinney, Siddharth Patel, Conroy Sun, and Gaurav Sahay, Lipid nanoparticle-delivered chemically modified mRNA restores chloride secretion in cystic fibrosis. Molecular Therapy, 2018 26(8):2034-2046.

https://www.sciencedirect.com/science/article/pii/S152500161830217X

Ashwani Narayana, Justin S Plaut, Barmak Mostofian, Siddharth Patel, Peter Kwak, Conroy Sun, Kerry McPhail, Daniel M Zuckerman, Sadik C Esener, Gaurav Sahay, Supramolecular self assembly of nanodrill-like structures for intracellular delivery. Journal of Controlled Release, 2018 282(28):76-89.

https://www.sciencedirect.com/science/article/pii/S0168365918301184?via%3Dihub

2017

Siddharth Patel, Ashwani Narayana, Emily Robinson, Allison Duross, Conroy Sun, Cosmin Minhai, Kerry E. Murphy-Benenato, Orn Almarsson, and Gaurav Sahay, Boosting intracellular delivery of lipid nanoparticle-encapsulated mRNA. Nano Letters, 2017 17(9): 5711-5718.

http://pubs.acs.org/doi/abs/10.1021/acs.nanolett.7b02664

2016

Anna Brown, Siddharth Patel, Carl Ward, Anna Lorenz, Mauren Ortiz, Allison DuRoss, Fabian Wieghardt, Amanda Esch, Elsje. G. Otten, Laura M. Heiser, Viktor I.  Korolchuk, Conroy Sun, Sovan Sarkar, and Gaurav Sahay, PEG-lipid micelles enable cholesterol efflux in Niemann Pick Type C1 disease-based lysosomal storage disorder. Scientific Reports, 2016 6, 31750.

https://www.nature.com/articles/srep31750

Martin T. King, Cesare H. Jenkins, Conroy Sun, Colin M. Carpenter, Xiaowei Ma, Kai Cheng, Quynh Le, John Sunwoo, Zhen Cheng, Guillem Pratx, and Lei Xing, Flexible radioluminescence imaging for FDG-guided surgery. Medical Physics, 2016 43(10), 5298-5306.

http://onlinelibrary.wiley.com/doi/10.1118/1.4961745/full

2015

Martin T. King, Colin M. Carpenter, Conroy Sun, Xiaowei Ma, Quynh Le, John Sunwoo, Zhen Cheng, Guillem Pratx, and Lei Xing, A comparative evaluation of CCD-based beta imaging and Cerenkov luminescence imaging for FDG-guided surgery. Journal of Nuclear Medicine, 2015 56(9) 1458-1464.

http://jnm.snmjournals.org/content/56/9/1458.short

Olga Volotskova, Conroy Sun, Jason H. Stafford, Ai Leen Koh, Xiaowei Ma, Zhen Cheng, Bianxiao Cui, Guillem Pratx, and Lei Xing, Efficient Radioisotope Energy Transfer (RET) by Gold Nanoclusters for Molecular Imaging. Small, 2015 11(32): 4002-4008.

http://onlinelibrary.wiley.com/doi/10.1002/smll.201500907/full

Raiyan Zaman, Hisanori Kosuge, Colin Carpenter, Conroy Sun, Michael McConnell, and Lei Xing, Scintillating balloon-enabled fiber-optic system for radionuclide imaging of atherosclerotic plaques. Journal of Nuclear Medicine, 2015 56(5): 771-777.

http://jnm.snmjournals.org/content/56/5/771.short

Dominik Naczynski, Conroy Sun, Silvan Turkan, Cesare Jenkins, Ai Leen Koh, Debra Ikeda, Guillem Pratx, and Lei Xing, X-ray Induced Shortwave Infrared Biomedical Imaging Using Rare-Earth Nanoprobes. Nano Letters, 2015 15(1): 96-102.

http://pubs.acs.org/doi/abs/10.1021/nl504123r

2014 – 2009

Colin Carpenter, Xiaowei Ma, Hongguang Liu, Conroy Sun, Guillem Pratx, Jing Wang, Sanjiv S. Gambhir, Lei Xing, and Zhen Cheng, Cerenkov Luminescence Endoscopy: Improved Molecular Sensitivity with β-Emitting Radiotracers. Journal of Nuclear Medicine, 2014 55(11): 1905-1909.

http://jnm.snmjournals.org/content/55/11/1905.short

Cheng Wang, Olga Volotskova, Kuangda Lu, Moiz Ahmad, Conroy Sun, Lei Xing, and Wenbin Lin, Synergistic Assembly of Heavy Metal Clusters and Luminescent Organic Bridging Ligands in Metal-organic Frame-works for Highly Efficient X-ray Scintillation. Journal of the American Chemical Society, 2014 136(17):6171-6174.

http://pubs.acs.org/doi/abs/10.1021/ja500671h

Yasuko Osakada, Guillem Pratx, Conroy Sun, Masanori Sakamoto, OlgaVolotskova, Qunxiang Ong, Toshiharu Teranishi, Yoshie Harada, Lei Xing, and Bianxiao Cui, X-ray induced optical luminescence via bio-molecule directed metal clusters. Chemical Communications, 2014 50(27):3549-3551.

http://pubs.rsc.org/-/content/articlelanding/2014/cc/c3cc48661c

Guillem Pratx, Kai Chen, Conroy Sun, Colin Carpenter, and Lei Xing, Super-resolution radioluminescence microscopy by reconstructing the ionization track. Journal of Nuclear Medicine, 2013 54(10):1841-1846.

http://jnm.snmjournals.org/content/54/10/1841.short

Guillem Pratx, Kai Chen, Conroy Sun, Lynn Martin, Colin Carpenter, and Lei Xing, Radioluminescence microscopy reveals radiotracer uptake in single living cells. PLOS ONE, 2012 7(10):e46285.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046285

Hongguang Liu, Colin Carpenter, Han Jiang, Guillem Pratx, Conroy Sun, Michael P. Buchin, Sanjiv S. Gambhir, Lei Xing, and Zhen Cheng, Intraoperative imaging of tumors using Cerenkov luminescence endoscopy: a feasibility experimental study. Journal of Nuclear Medicine, 2012 53(10): 1579-1584.

http://jnm.snmjournals.org/content/53/10/1579.short

Colin Carpenter, Conroy Sun, Guillem Pratx, Hongguang Liu, Zhen Cheng, and Lei Xing, Radioluminescent nanophosphors enable multiplexed small animal imaging. Optics Express, 2012 20(11): 11598-11604.

https://www.osapublishing.org/oe/fulltext.cfm?uri=oe-20-11-11598&id=233138

Conroy Sun, Colin Carpenter, Guillem Pratx, and Lei Xing, Facile synthesis of amine functionalized Eu3+-doped La(OH)3 nanophosphors for bioimaging. Nanoscale Research Letters, 2011 6(24).

https://link.springer.com/article/10.1007/s11671-010-9768-x

Conroy Sun, Guillem Pratx, Colin Carpenter, Hongguang Liu, Zhen Cheng, Sanjiv Sam Gambhir, and Lei Xing, Synthesis and radioluminescence of PEGylated Eu3+-doped nanophosphors as bioimaging probes. Advanced Materials, 2011 23(24): H195-199.

http://onlinelibrary.wiley.com/doi/10.1002/adma.201100919/full

Colin Carpenter, Guillem Pratx, Conroy Sun, and Lei Xing, Limited-angle X-ray luminescence tomography: methodology and feasibility study. Physics in Medicine and Biology, 2011 56(12): 3487-3502.

http://iopscience.iop.org/article/10.1088/0031-9155/56/12/003/meta

Guillem Pratx, Colin Carpenter, Conroy Sun, and Lei Xing, X-ray luminescence computed tomography via selective excitation: a feasibility study. IEEE Transactions on Medical Imaging, 2010, 29(12): 1992-1999.

http://ieeexplore.ieee.org/abstract/document/5504516/

Guillem Pratx, Colin Carpenter, Conroy Sun, Ravi P Rao, and Lei Xing, Tomographic molecular imaging of X-ray-excitable nanoparticles. Optics Letters, 2010 35(20): 3345-3347.

http://onlinelibrary.wiley.com/doi/10.1118/1.3457332/full

Colin Carpenter, Conroy Sun, Guillem Pratx, Ravi P Rao, and Lei Xing, Hybrid X-ray/Optical Luminescence Imaging; Characterization of Experimental Conditions. Medical Physics, 2010 37(8): 4011-4018.

http://onlinelibrary.wiley.com/doi/10.1118/1.3457332/full

James O. Park, Zachary Stephen, Conroy Sun, Omid Veiseh, Forrest Kievit, Chen Fang, Matthew Leung, Hyejung Mok, and Miqin Zhang, Glypican-3 targeting of liver cancer cells using multifunctional nanoparticles. Molecular Imaging, 2011 10(1): 69-77.

http://journals.sagepub.com/doi/abs/10.2310/7290.2010.00048

Conroy Sun, Kim Du, Chen Fang, Narayan Bhattarai, Omid Veiseh, Donghoon Lee, Richard G. Ellenbogen, Buddy Ratner, and Miqin Zhang, PEG-mediated synthesis of highly dispersive multifunctional superparamagnetic nanoparticles: their physiochemical properties and function in vivo. ACS Nano, 2010 4(4): 2402-2410.

http://pubs.acs.org/doi/abs/10.1021/nn100190v

Michelle Lee, Omid Veiseh, Narayan Bhattarai, Conroy Sun, Stacey J. Hansen, Sally Ditzler, Sue Knoblaugh, Donghoon Lee, Richard Ellenbogen, Miqin Zhang, and James Olson, Rapid pharmacokinetic and biodistribution studies for nanoparticles: application to chlorotoxin-coated iron oxide nanoparticles. PLOS ONE, 2010 5(3): e9536.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009536

Omid VeisehŦ, Conroy SunŦ, Chen Fang, Narayan Bhattarai, Jonathan Gunn, Forrest Kievit, Kim Du, Barbara Pullar, Donghoon Lee, Richard Ellenbogen, James Olson, and Miqin Zhang, Specific targeting of tumors with an optical/MR imaging nanoprobe across the blood brain barrier. Cancer Research, 2009 69(15): 6200-6207. ŦContributed equally.

http://cancerres.aacrjournals.org/content/69/15/6200.short

Chen Fang, Narayan Bhattarai, Conroy Sun, and Miqin Zhang, Functionalized nanoparticles with long-term stability in biological media. Small, 2009 5(14): 1637-1641.

http://onlinelibrary.wiley.com/doi/10.1002/smll.200801647/full

Omid Veiseh, Jonathan W. Gunn, Forrest Kievit, Conroy Sun, Chen Fang, Jerry S.H. Lee, and Miqin Zhang, Inhibition of tumor cell invasion with chlorotoxin-bound superparamagnetic nanoparticles. Small, 2009 5(2): 256-264.

http://onlinelibrary.wiley.com/doi/10.1002/smll.200800646/full

Prior to 2009

Conroy Sun, Chen Fang, Zachary Stephen, Omid Veiseh, Stacey Hansen, Donghoon Lee, Richard G. Ellenbogen, Jim Olson, and Miqin Zhang, Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparticles. Nanomedicine, 2008 3(4): 495-505.

https://www.futuremedicine.com/doi/abs/10.2217/17435889.3.4.495

Conroy Sun, Jerry S.H. Lee, and Miqin Zhang, Magnetic Nanoparticles in MR Imaging and Drug Delivery. Advanced Drug Delivery Reviews, 2008 60(11): 1252-1265.

http://www.sciencedirect.com/science/article/pii/S0169409X08001014

Jonathan Gunn, Herschel Wallen, Omid Veiseh, Conroy Sun, Chen Fang, Jianhong Cao, Cassian Yee, and Miqin Zhang, A multimodal targeting nanoparticle for selectively labeling T cells. Small, 2008 4(6): 712-715.

http://onlinelibrary.wiley.com/doi/10.1002/smll.200701103/full

Conroy Sun, Omid Veiseh, Jonathan Gunn, Chen Fang, Stacey Hansen, Donghoon Lee, Raymond Sze, Richard G. Ellenbogen, Jim Olson, and Miqin Zhang, In Vivo MRI Detection of Gliomas by Chlorotoxin-Conjugated Superparamagnetic Nanoprobes. Small, 2008 4(3): 372-379.

http://onlinelibrary.wiley.com/doi/10.1002/smll.200700784/full

Conroy Sun, Raymond Sze, and Miqin Zhang, Folic acid-PEG conjugated Superparamagnetic nanoparticles for targeted cellular uptake and detection by MRI. Journal of Biomedical Materials Research. Part A, 2006 78(3): 550-557.

http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.30781/full

Nathan Kohler, Conroy Sun, Alex Fichtenholtz, Jonathan Gunn, Chen Fang, and Miqin Zhang, Methotrexate immobilized poly(ethylene glycol) magnetic nanoparticles for MR imaging and drug delivery. Small, 2006 2(6): 785-792.

http://onlinelibrary.wiley.com/doi/10.1002/smll.200600009/full

Nathan Kohler, Conroy Sun, Jassy Wang, and Miqin Zhang, Methotrexate-modified superparamagnetic nanoparticles and their intracellular uptake into human cancer cells. Langmuir, 2005 21(19): 8858-8864.

http://pubs.acs.org/doi/abs/10.1021/la0503451

Omid Veiseh, Conroy Sun, Jonathan Gunn, Nathan Kohler, Patrik Gabikian, Donghoon Lee, Narayan Bhattarai, Richard Ellenbogen, Raymond Sze, Andrew Hallahan, Jim Olson, and Miqin Zhang, Optical and MRI multifunctional nanoprobe for targeting gliomas. Nano Letters, 2005 5(6): 1003-1008.

http://pubs.acs.org/doi/abs/10.1021/nl0502569

Yong Zhang, Conroy Sun, Nathan Kohler, and Miqin Zhang, Self-assembled coatings on individual monodisperse magnetite nanoparticles for efficient intracellular uptake, Biomedical Microdevices, 2004 6(1): 33-40.

https://link.springer.com/article/10.1023%2FB%3ABMMD.0000013363.77466.63