{"id":1644,"date":"2015-03-30T11:26:09","date_gmt":"2015-03-30T18:26:09","guid":{"rendered":"http:\/\/blogs.oregonstate.edu\/psquared\/?page_id=1644"},"modified":"2025-04-02T12:32:59","modified_gmt":"2025-04-02T19:32:59","slug":"welcome-to-protein-portraits-2015","status":"publish","type":"page","link":"https:\/\/blogs.oregonstate.edu\/psquared\/","title":{"rendered":"Welcome to Protein Portraits at Oregon State University"},"content":{"rendered":"<p>Hello and welcome to Protein Portraits, the Oregon State University Honors College course that\u00a0adds\u00a0paint brushes and computer art to the appreciation of protein molecules and their assemblies. \u00a0We build protein molecules\u00a0as we imagine\u00a0them,\u00a0depicting them\u00a0as reflections of not only experimental science but of our living experience in the world.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-2736 size-large\" src=\"https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/150\/files\/2021\/03\/Collage-2021-1024x282.png\" alt=\"\" width=\"640\" height=\"176\" srcset=\"https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/150\/files\/2021\/03\/Collage-2021-1024x282.png 1024w, https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/150\/files\/2021\/03\/Collage-2021-300x83.png 300w, https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/150\/files\/2021\/03\/Collage-2021-768x212.png 768w, https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/150\/files\/2021\/03\/Collage-2021-1536x424.png 1536w, https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/150\/files\/2021\/03\/Collage-2021.png 1784w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<h2>Science before art. \u00a0Or does art come before science?<\/h2>\n<p>We know from the recent history of molecular biology that new discoveries about proteins are oftentimes inspired by knowledge of the 3D structure of the protein. \u00a0Lots of effort therefore goes into gaining 3D knowledge. \u00a0But the knowledge is inherently limited in the same way that a series of snapshots is less informative than a whole film, and a film, marvelous as it may be to watch, is only an edited compilation of many recording sessions. \u00a0At a certain point we have to admit that despite our possession of the 3D structure of a molecule, we have very large gaps in knowledge. \u00a0We doodle on paper or in our minds to organize our question marks and sketch out hypothetical pictures of reality that hopefully guide us toward fruitful new experiments. In short, art meets science every single time we think about protein molecules. \u00a0We depend on art to make the invisible visible to our very thinking.<\/p>\n<p>In our course, each protein artist&#8217;s work will claim, &#8220;<em>This<\/em> is what a\u00a0protein\u00a0<em>is<\/em> according to me, the artist&#8221;. \u00a0That is the aim of our course. \u00a0Ten weeks. \u00a0They go by quickly.<\/p>\n<p>These weeks are not solely a mad rush to graph out the latest science, though some students with technical orientations might want to do that. \u00a0Nor is it a race to dazzle the world with sensory stimulation that spills from one&#8217;s emotions about proteins and related molecules such as poisons and therapeutics, though some artists with deep feelings may be so inspired. \u00a0For most, these ten weeks are an opportunity to feel and think <em>at the same time<\/em>. \u00a0There are mysteries out there, and like art detectives we do have some facts to help us begin our case studies.<\/p>\n<p>Art, in its ineluctable way, helps us embrace our factual situation creatively &#8212; with deeper humanity . Kandinsky&#8217;s \u00a0abstract paintings from a hundred years ago were seen by many at the time as an unjustifiable breaking away from facts and reality. But did his detailed studies not reveal that there is much more to the world that we had missed before? \u00a0In the ten weeks ahead, that may be inspiration enough for guiding our protein artists to try something new.<\/p>\n<div style=\"width: 412px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/9\/98\/Vassily_Kandinsky%2C_1913_-_Color_Study%2C_Squares_with_Concentric_Circles.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"\" src=\"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/9\/98\/Vassily_Kandinsky%2C_1913_-_Color_Study%2C_Squares_with_Concentric_Circles.jpg\" alt=\"Squares and Circles. Oil, by Wassily Kandinsky 1913.\" width=\"402\" height=\"303\" \/><\/a><p class=\"wp-caption-text\">Squares and Circles. Oil, by Wassily Kandinsky 1913.<\/p><\/div>\n<h2>Go forth and create<\/h2>\n<p>No doubt, protein molecules are currently well-described by science. \u00a0But what is typically found to be missing in every scientific endeavor are the nuances revealed when boundaries are broken and new realizations come to the forefront. \u00a0Art is a process that can open the collective imagination to spur those changes. \u00a0In this sense, art precedes science in the way that imagination precedes art.<\/p>\n<p>Below are three works of protein art left to the world by one of the great stylists of protein portraiture, Irving Geis, 1908-1997. \u00a0Take an especially long look at the first one. \u00a0As the first protein to have its 3D structure revealed at the molecular level, myoglobin could not be compared to much of anything in human experience. \u00a0It took artistic finesse to imprint the structure into our mind&#8217;s eye. \u00a0And in a friendly getting-to-know-you gesture, Geiss chose to have the myoglobin molecule look back at us with it&#8217;s eyelike iron center.<\/p>\n<h4><a href=\"http:\/\/www.hhmi.org\/sites\/default\/files\/News\/2000\/Geis\/0182.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"http:\/\/www.hhmi.org\/sites\/default\/files\/News\/2000\/Geis\/0182.jpg\" alt=\"\" width=\"243\" height=\"214\" \/><\/a> Myoglobin<\/h4>\n<p>\u00a92000 Howard HughesMedical Institute<\/p>\n<h4><a href=\"http:\/\/www.hhmi.org\/sites\/default\/files\/News\/2000\/Geis\/0570.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"http:\/\/www.hhmi.org\/sites\/default\/files\/News\/2000\/Geis\/0570.jpg\" alt=\"\" width=\"237\" height=\"298\" \/><\/a> Cytochrome c<\/h4>\n<p>\u00a92000 Howard Hughes Medical Institute<\/p>\n<h4><a href=\"http:\/\/www.hhmi.org\/sites\/default\/files\/News\/2000\/Geis\/0562.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone \" src=\"http:\/\/www.hhmi.org\/sites\/default\/files\/News\/2000\/Geis\/0562.jpg\" width=\"237\" height=\"246\" \/><\/a> Tomato bushy stunt virus<\/h4>\n<p>\u00a92000 Howard Hughes\u00a0Medical Institute<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hello and welcome to Protein Portraits, the Oregon State University Honors College course that\u00a0adds\u00a0paint brushes and computer art to the appreciation of protein molecules and their assemblies. \u00a0We build protein molecules\u00a0as we imagine\u00a0them,\u00a0depicting them\u00a0as reflections of not only experimental science &hellip; <a href=\"https:\/\/blogs.oregonstate.edu\/psquared\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":196,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1644","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blogs.oregonstate.edu\/psquared\/wp-json\/wp\/v2\/pages\/1644","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.oregonstate.edu\/psquared\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blogs.oregonstate.edu\/psquared\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.oregonstate.edu\/psquared\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.oregonstate.edu\/psquared\/wp-json\/wp\/v2\/comments?post=1644"}],"version-history":[{"count":68,"href":"https:\/\/blogs.oregonstate.edu\/psquared\/wp-json\/wp\/v2\/pages\/1644\/revisions"}],"predecessor-version":[{"id":3056,"href":"https:\/\/blogs.oregonstate.edu\/psquared\/wp-json\/wp\/v2\/pages\/1644\/revisions\/3056"}],"wp:attachment":[{"href":"https:\/\/blogs.oregonstate.edu\/psquared\/wp-json\/wp\/v2\/media?parent=1644"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}