Marilyn Mackiewicz Google Scholar
Publications
Mackiewicz, M.R.; Hosbein, K.; Mason, D.; and Ajjarapu, R. “Integrating Scientific Growth and Professional Development Skills in Research Environments to Aid in the Persistence of Marginalized Students”. J. Chem. Educ. 2023, 100, 1, 199–208.
Marquart, Grant. W; Stoddard, Jonathan; McGill, Trevor. J.; Kinnison, Karen.; Zhou, Felicia.; Hugo, Richard.; Ryals, Renee.; Schubert, S.; Mackiewicz, M.R. “Increasing the Efficacy of Gold Nanorod Uptake in Stem Cell-Derived Therapeutic Cells: Implications for Stem Cell Labeling and Optical Coherence Tomography Imaging”. ACS Appl. Nano Mater. 2022, 5, 5, 6995–7008.
Dent, S. E.; King, D. P.; Osterberg, V. R.; Adams, E. K.; Mackiewicz, M. R.; Weissman, T. A.; Unni, V. K. “Phosphorylation of the aggregate-forming protein alpha-synuclein on serine-129 inhibits its DNA-bending properties”. Journal of Biological Chemistry (5.157), 2022, 298 (2), 101552.
Marquart, G. M. S., J.; McGill, T.J.; Kinnison, K.; Zhou, F.; Hugo, R.; Ryals, R.; Schubert, S.; Mackiewicz, M.R. The Impact of Surface Chemistry on Gold Nanorod Uptake in Stem Cell-derived Therapeutic Cells. ChemRxiv Preprint 2021. http://doi.org/10.33774/chemrxiv-2021-fhcv5
Cunningham, B.; Engstrom, A. M.; Harper, B. J.; Harper, S. L.; Mackiewicz, M. R., Silver Nanoparticles Stable to Oxidation and Silver Ion Release Show Size-Dependent Toxicity In Vivo. Nanomaterials 2021, 11 (6), 1516.
Marriott, L. K.; Raz Link, A.; Anitori, R. P.; Blackwell, E. A.; Blas, A.; Brock, J.; Burke, T. K.; Burrows, J. A.; Cabrera, A. P.; Helsham, D.; Liban, L. B.; Mackiewicz, M. R.; Maruyama, M.; Milligan-Myhre, K. C. A.; Panelinan, P. J. C.; Hattori-Uchima, M.; Reed, R.; Simon, B. E.; Solomon, B.; Trinidad, A. M. O.; Wyatt, L. R.; Delgado Covarrubias, A.; Zell, A.; Keller, T. E.; Morris, C.; Crespo, C. J., Supporting Biomedical Research Training for Historically Underrepresented Undergraduates Using Interprofessional, Nonformal Education Structures. JoSoTL 2021, 21 (1), 241-286.
Engstrom A. M; F. R., Marquart G. W; Baio J.E; Mackiewicz M.R.; Harper S.L. Size-Dependent Interactions of Lipid-Coated Gold Nanoparticles: Developing a Better Mechanistic Understanding Through Model Cell Membranes and in vivo Toxicity. Int. J. Nanomedicine 2020,15, 4091-4104.
Engstrom, A. M.; Wu, H.; Mackiewicz, M. R.; Harper, S. L. Controlling Silver Ion Release of Silver Nanoparticles with Hybrid Lipid Membranes with Long-Chain Hydrophobic Thiol Anchors Decreases in vivo Toxicity, IJERA 2020, 10, 12-28.
Miesen, T.J.; Engstrom, A. M.; Frost, D.C.; Ajjarapu, R.; Ajjarapu, R.; Nieves Lira, C.; Mackiewicz, M. R. Hybrid lipid-membrane coating “shape-lock” silver nanoparticles to prevent surface oxidation and silver ion dissolution. RSC Advances 2020, 10, 15677-15693.
Aggarwal, A.; Samaroo, D.; Jovanovic, I. R.; Singh, S.; Tuz, M. P.; Mackiewicz, M. R. Porphyrinoid-based photosensitizers for diagnostic and therapeutic applications: An update. Journal of Porphyrins and Phthalocyanines Preliminary Pharmacological Characterization 2019, 23, (07n08), 4704-4715.
Virca, C. N.; Winter, H. M.; Goforth, A. M.; Mackiewicz, M. R.; McCormick, T. M.Photocatalytic water reduction using a polymer-coated carbon quantum dot sensitizer and a nickel nanoparticle catalyst. Nanotechnology 2017, 28 (19), 195402.
Hamilton, D. J, Cai, Y.; Kaur, R.; Marquart, G. W.; Mackiewicz, M. R.; Reed, S. M. Hybrid Lipid-coated Nanoparticles as Probes for Membrane Binding. Chemical and Synthetic Approaches to Membrane Proteins 2016. (in press)
Ho Wu, R.; Nguyen, T. P.; Marquart, G. M.; Miesen, T. J.; Mau, T.; Mackiewicz, M. R. A facile route to tailoring peptide-stabilized gold nanoparticles using glutathione as a synthon. Molecules 2014, 19 (5), 6754-6775.
Sinche, F., Ho Wu, R., Gowrishankar, M., Marquart, G. W., Mackiewicz, M. R., Harper, B. and S. L. Harper. The impact of synthesis method and purity on the toxicity of glutathione-coated gold nanoparticles. Nanomaterials 2014, 4 (2), 355-371.
Norris, C.; Rencit, P. R.; Mackiewicz, M. R.; Reed, S. M. A Simple Synthesis of Gold-Core, Silver-Shell Nanoeggs Using Minimal Formaldehyde. Chem. Mater. 2010, 22 (12), 3637–3645.
Mackiewicz, M. R.; Hodges, H. L.; Brown, A. L.; Reed. S. M. Nanoparticle-Enhanced Assay for Detection of C-reactive Protein with Phosphatidylcholine Ligands. J. Phys. Chem. B. 2010, 114 (16), 5556–5562.
Situala, S.; Mackiewicz, M. R.; Reed. S. M. Gold Nanoparticles Become Stable to Cyanide Etch when Coated with Hybrid Lipid Bilayers. Chem. Commun. 2008, 3013–3015.
Mackiewicz, M. R.; Ayres, B. R.; Reed, S. M. Reversible, Reagentless Solubility Changes in Phosphatidylcholine-stabilized Gold Nanoparticles. Nanotechnology 2008, 19, 115607-115613.
Rampersad, M. V.; Zuidema, E.; Ernsting, J. M.; van Leeuwen, P. W. N. M.; Darensbourg, M. Y. CO and Ethylene Migratory Insertion Reactions and Copolymerization Involving Palladium Complexes of a NiN2S2 Metallodithiolate Ligand. Organometallics 2007, 26 (4), 783-792.
Phelps, A. L.; Rampersad, M. V.; Fitch, S. B.; Darensbourg, D. J.; Darensbourg, M. Y. Kinetic Study of the Ring-Opening Process in Tungsten Carbonyl Complexes Containing Hemilabile Metallodithiolate Ligands. Inorg. Chem. 2006, 45 (1), 119-126.
Jeffery, S. P.; Green, K. N.; Rampersad, M. V.; Darensbourg, M. Y. NiN2S2 Complexes as Metallodithiolate Ligands to RhI, RhII and RhIII. Dalton Trans. 2006, 35, 4244-4252.
Rampersad, M. V.; Jeffery, S. P.; Golden, M. L.; Lee, J.; Reibenspies, J. H.; Darensbourg, D. J.; Darensbourg, M. Y. Characterization of Steric and Electronic Properties of NiN2S2 Complexes as S-Donor Metallodithiolate Ligands. J. Am. Chem. Soc. 2005, 127 (49), 17323-17334.
Rampersad, M. V.; Jeffery, S. P.; Reibenspies, J. H.; Ortiz, C. G.; Darensbourg, D. J.; Darensbourg, M. Y. N2S2Ni Metallothiolates as a Class of Ligands that Support Organometallic and Bioorganometallic Reactivity. Angew. Chem. Int. Ed. 2005, 44, 1217-1220.
Golden, M. L.; Whaley, C. M.; Rampersad, M. V.; Reibenspies, J. H.; Hancock, R. D.; Darensbourg, M. Y. N2S2Ni Metallodithiolate Complexes as Ligands: Structural and Aqueous Solution Quantitative Studies of the Ability of Metal Ions to Form M-S-Ni Bridges to Mercapto Groups Coordinated to Nickel(II): Implications for Acetyl coA Synthase. Inorg. Chem. 2005, 44 (4), 875-883.
Golden, M. L.; Rampersad, M. V.; Reibenspies, J. H.; Darensbourg, M. Y. Capture of NiII, CuI and ZnII by Thiolate Sulfurs of an N2S2Ni complex: A role for a Metallothiolate Ligand in the Acetyl-coenzyme A Synthase Active Site. Chem. Commun. 2003, 15, 1824-1825.
Zhao, X.; Chiang, C.i; Miller, M. L.; Rampersad, M. V.; Darensbourg, M. Y. Activation of Alkenes and H2 by [Fe]-H2ase Model Complexes. J. Am. Chem. Soc. 2003, 125, 518-524.
Efange, S. M. N.; Tu, Z.; von Hohenberg, K.; Francesconi, L. C; Howell, R. C.; Rampersad, M. V.; Todaro, L. J.; Papke, R. L.; Kung, M.-P. 2-(2-Piperidyl)- and 2-(2-Pyrrolidyl)chromans as Nicotine Agonists: Synthesis and Preliminary Pharmacological Characterization. J. Med. Chem. 2001, 44, 4704-4715.
Presentations
261st ACS National Meeting, April 5-16, 2021, Mackiewicz, M. R.* “Solving the mystery between silver and silver nanoparticles: Who’s toxic?”
259th ACS National Meeting & Exposition, Philadelphia, PA, United States, March 22-26, 2020, Zhou, Felica; Caldwell, Adam; Mackiewicz, M. R.* “Optimizing gold nanoparticle-fluorophore Interactions to minimize fluorescence quenching.”
259th ACS National Meeting & Exposition, Philadelphia, PA, United States, March 22-26, 2020, Paulin, Kim; Engstrom, Arek M.; Mackiewicz, M. R.* ”Robust nickel nanoparticles shielded from surface oxidation.”
74th Northwest Regional Meeting of the American Chemical Society, Portland, OR, United States, June 16-19, 2019, Sawab, Hamzah; Engstrom, Arek M.; Faase, Ryan; Harper, Stacey L.; Baio, Joe; Mackiewicz, M. R.* “Tuning the curvature of hybrid lipid-coated gold nanoparticles to investigate their role in toxicity.”
74th Northwest Regional Meeting of the American Chemical Society, Portland, OR, United States, June 16-19, 2019, Marquart, Grant W.; Zhou, Felicia; * Mackiewicz, M. R.* “Teasing apart nanoparticle-protein interactions with hybrid lipid-coated gold nanoparticles.”
74th Northwest Regional Meeting of the American Chemical Society, Portland, OR, United States, June 16-19, 2019, Engstrom, Arek M.; Wu, Henry; Mackiewicz, M. R.*; Harper, Stacey L., “Hybrid lipid-coated silver nanoparticles with long-chain hydrophobic thiol surface coatings show decreased toxicity compared to those without robust surface coatings.”
74th Northwest Regional Meeting of the American Chemical Society, Portland, OR, United States, June 16-19, 2019, Mackiewicz, M. R.* “Evolving nanotechnologies for ophthalmology applications.”
257th ACS National Meeting & Exposition, Orlando, FL, United States, Mar. 31-Apr. 4, 2019, Wu, Henry; Engstrom, Arek; Harper, Bryan; Harper, Stacey; * Mackiewicz, M. R.* “Teasing apart how specific features of silver nanoparticles contribute to toxicity.”
257th ACS National Meeting & Exposition, Orlando, FL, United States, Mar. 31-Apr. 4, 2019, Sawab, Hamzah; Mackiewicz, M. R.* ”Design of cholera toxin B-conjugated gold nanoparticles to target retinal ganglion cells in the eye.”
257th ACS National Meeting & Exposition, Orlando, FL, United States, Mar. 31-Apr. 4, 2019, Marquart, Grant W.; Zhou, Felicia; Mackiewicz, M. R.* “Investigating nanoparticle-protein interactions with hybrid lipid-coated gold nanoparticles.”
257th ACS National Meeting & Exposition, Orlando, FL, United States, Mar. 31-Apr. 4, 2019, Adams, Eleanor K.; Mackiewicz, M. R.* “Studying beta amyloid oligomer formation using fluorescence anisotropy and atomic force microscopy.”
256th ACS National Meeting & Exposition, Boston, MA, United States, August 19-23, 2018, Sawab, Hamzah; Mackiewicz, M. R.* “Design of nickel nanoparticles for X-ray fluorescence microscopy to visualize cellular metal ion concentrations.”
256th ACS National Meeting & Exposition, Boston, MA, United States, August 19-23, 2018, Mackiewicz, M. R.*., “Engaging nanoparticle-cell interactions through “smart” design.”
256th ACS National Meeting & Exposition, Boston, MA, United States, August 19-23, 2018, Wu, Henry; Demchenko, Diana; Stedman, Kenneth M.; Mackiewicz, M. R.* “Tuning the surface architecture of silver nanoparticles for use as anti-viral agents.”
73rd Northwest Regional Meeting of the American Chemical Society, Richland, WA, United States, June 24-27, 2018, Mackiewicz, M. R.* “Integrating professional development into research experiences.”
73rd Northwest Regional Meeting of the American Chemical Society, Richland, WA, United States, June 24-27, 2018, Mackiewicz, M. R.*; Adams, Eleanor, “Metallodithiolate ligands for reversing metal ion induced aggregation of beta amyloid.”
73rd Northwest Regional Meeting of the American Chemical Society, Richland, WA, United States, June 24-27, 2018, Wu, Henry; Demchenko, Diana; Stedman, Kenneth M.; Mackiewicz, M. R.* “Tuning the surface architecture of silver nanoparticles for use as anti-viral agents.”
73rd Northwest Regional Meeting of the American Chemical Society, Richland, WA, United States, June 24-27, 2018, Mackiewicz, M. R.*; Sawab, Hamzah, “Design of nickel nanoparticles for x-ray fluorescence microscopy to visualize cellular metal ion Concentrations.”
255th ACS National Meeting & Exposition, New Orleans, LA, United States, March 18-22, 2018, Mackiewicz, M. R.*; Kinnison, Karen; Stoddard, Jonathan; Hugo, Richard; McGill, Trevor, “Nanomaterials for enhancing the resolution of optical coherence tomography in the retina.”
255th ACS National Meeting & Exposition, New Orleans, LA, United States, March 18-22, 2018, Kinnison, Karen; Wilsey, Laura; Fortune, Brad; * Mackiewicz, M. R.* “Hybrid lipid-coated gold nanoparticles for studying axonal transport mechanisms in the retina.”
255th ACS National Meeting & Exposition, New Orleans, LA, United States, March 18-22, 2018, Adams, Eleanor K.; Mackiewicz, M. R.* “Metallodithiolate ligands for reversing metal ion induced aggregation of beta amyloid.”
72nd Northwest Regional Meeting of the American Chemical Society, Corvallis, OR, United States, June 25-28, 2017, Kinnison, Karen; Mackiewicz, M. R.*; “Engaging nanoparticle-cell interactions through “smart” design.”
72nd Northwest Regional Meeting of the American Chemical Society, Corvallis, OR, United States, June 25-28, 2017, Reed, Julie F.; Demchenko, Diana; Stedman, Kenneth M.; Mackiewicz, M. R.*; “Exploring the effects of differentially shielded silver nanoparticles on a robust thermophilic virus.”
253rd ACS National Meeting & Exposition, San Francisco, CA, United States, April 2-6, 2017, Mackiewicz, M. R.*; Miesen, Thomas J., “Hybrid lipid-coated silver nanoparticles differentially shielded from Ag+ release.”
253rd ACS National Meeting & Exposition, San Francisco, CA, United States, April 2-6, 2017, Kinnison, Karen L.; Marquart, Grant W.; Mackiewicz, M. R.* “Tailoring the surface architecture of gold nanoparticles to engage nanoparticle-cell interactions.”
252nd ACS National Meeting & Exposition, Philadelphia, PA, United States, August 21-25, 2016, Mackiewicz, M. R.*;; Stoddard, Jonathan; Jia, Yali; Liu, Gangjun; Gao, Simon; Pechauer, Alex; Huang, David; McGill, Trevor, “Retinal cell labeling using hybrid lipid-coated gold nanorods.”
251st ACS National Meeting & Exposition, San Diego, CA, United States, March 13-17, 2016, Mackiewicz, M. R.*; Sanchez, Paco, “Robust hybrid membrane-coated nanoparticles for targeting tumors.”
251st ACS National Meeting & Exposition, San Diego, CA, United States, March 13-17, 2016, Tung, James; Mackiewicz, M. R.* “Help me get a job: The Portland Section’s approach to helping new graduates and working chemists find employment in chemistry.”
Abstracts of Papers, 249th ACS National Meeting & Exposition, Denver, CO, United States, March 22-26, 2015, Mackiewicz, M. R.*; Jorgenson, Brent D.; Costa, Erica A., “Modulating beta-amyloid (Ab) aggregation with metal ions and nanochelators.”
247th ACS National Meeting & Exposition, Dallas, TX, United States, March 16-20, 2014, Nguyen, Tan; Mackiewicz, M. R.* “Nanochelators for sensing and targeting iron in cancer cells.”
247th ACS National Meeting & Exposition, Dallas, TX, United States, March 16-20, 2014, Mackiewicz, M. R.*; Clifton, Molly, “Site-directed nanochelators for reversing metal-induced protein aggregation.”
246th ACS National Meeting & Exposition, Indianapolis, IN, the United States, September 8-12, 2013, Frost, Dane C.; Ross, Colin M.; Miesen, Thomas J.; Mackiewicz, M. R.* “Investigating beta-amyloid interactions with lipid-coated nanoparticles.”
246th American Chemical Society Meeting, September 8th, 2013, Indianapolis, IN. Mackiewicz, M. R.*. “Effect of metal ions and chelators in modulating beta amyloid aggregation and binding to biomimetic lipid-coated gold nanoparticles” (oral presentation)
242nd American Chemical Society Meeting, August 29th, 2011, Denver, CO. Mackiewicz, M. R.*. “Biocompatible nanochelators surface functionalized with phytochelatin peptide derivatives for metal chelation studies.” (oral presentation)
NORM172 ACS Northwest Regional Meeting, June 29th, 2011, Portland, OR. Mackiewicz, M. R.*. “Phytochelatin-based Gold Nanochelators for Metal Ion Detection and Chelation Studies”
66th Northwest Regional Meeting of the American Chemical Society, Portland, OR, United States, June 26-29, 2011, Wu, Rosina Ho; Gowrishankar, Meenambika; Azimi, Shauyaun Mackiewicz, M. R.* “Biocompatible Gold Nanomaterials for Chelation of Toxic Metals.”
Abstracts of Papers, 241st American Chemical Society Meeting, March 29th, 2011, Anaheim, CA. Mackiewicz, M. R.*, Ho Wu, Rosina; Mau, Theresa; Azimi, Shauyaun; and Sinche, Federico. “Multifunctional biocompatible iron and gold nanomaterials for metal chelation applications.”
Seminar at Oregon State University, February 9th, 2011, Corvallis, OR. Mackiewicz, M. R.*. “Nanoparticles as Mimics of Biological Membrane Structures.” (oral presentation)
238th American Chemical Society Meeting, August 15th, 2009, Washington , DC. Mackiewicz, M. R.*; Reed, Scott M. “C-reactive Protein Recognition by Phosphatidylcholine-stabilized Gold Nanoparticles.” (poster presentation)
Seminar at Colorado School of Mines and NREL, March 9th, 2010, Golden, CO. Mackiewicz, M. R.*; Reed, S. M. “Designing Nanoscale Architectures for Nanosensor Development.” (oral presentation)
238th American Chemical Society Meeting, August 15th, 2009, Washington , DC. Mackiewicz, M. R.*; Reed, Scott M. “C-reactive Protein Recognition by Phosphatidylcholine-stabilized Gold Nanoparticles.” (poster presentation)
237th American Chemical Society Meeting, March 22nd, 2009, Salt Lake City, UT. Mackiewicz, M. R.*; Reed, Scott M. “Recognition of C-reactive Protein by Phosphatidylcholine-stabilized Gold Nanoparticles.” (poster presentation)
Seminar at Michigan State University, January 26th, 2009, Lansing, MI. Mackiewicz, M. R.*; Reed, S. M. “Nanoparticles as Mimics of Biological Membrane Structures for Detection of C-Reactive Protein. (oral presentation)
Seminar at University of Colorado at Denver, January 29th, 2009, Denver, CO. Mackiewicz, M. R.*; Reed, S. M. “Nanoparticles as Mimics of Biological Membrane Structures for Detection of C-Reactive Protein. (oral presentation)
Seminar at University of Texas at San Antonio, February 3rd, 2009, San Antonio, TX. Mackiewicz, M. R.*; Reed, S. M. “Nanoparticles as Mimics of Biological Membrane Structures for Detection of C-Reactive Protein. (oral presentation)
235th American Chemical Society Meeting, April 6th, 2008, New Orleans, LA. Mackiewicz, M. R.*; Ayres, Benjamin R.; Joseph, Paul R.; Reed, Scott M. “PC-stabilized metal nanoparticles repeatedly phase-transfer from organic to aqueous solvents without added reagents or chemical modification.” (poster presentation)
3rd Annual Greener Nanoscience, March 10th, 2008, Hewlett-Parkard, Corvallis, OR. Mackiewicz, M. R.*; Sitaula, Sarita; Ayres, Benjamin R.; Reed, Scott M. “Lecithin-stabilized Gold Nanoparticles with Unique Phase Transfer Properties and their Reactivity to Thiol Exchange.” (poster presentation)
Hunter College Recruitment Seminar, October 26th, 2008. Hunter College, New York, NY. Rampersad, M. V.* “Development of NiN2S2 Complexes as Bidentate Ligands for Organometallic Chemistry.” (oral presentation)
International Conference on Biological Inorganic Chemistry, July 31st, 2005. Ann Arbor, Michigan. Rampersad, M. V.*; Darensbourg, Marcetta Y. “Bioinspired Metallodithiolate Ligands To facilitate C-C Coupling Reactions at Palladium.” (poster presentation).
229th American Chemical Society Meeting, March 13, 2004, San Diego, CA. Rampersad, M. V.*; Jeffery, Stephen P. Golden, Melissa L.; Ortiz, Cesar G.; Darensbourg, Donald J.; Darensbourg, Marcetta Y. “Development of Metal Dithiolate Complexes as Bidentate Ligands for Organometallic Chemistry Inspired by Acetyl Coenzyme A Synthase.” (poster presentation)
Industry-University Cooperative Chemistry Program IUCCP Symposium, October 18, 2004, Texas A & M University, College Station, TX. Rampersad, M. V.*; Jeffery, Stephen P.; Golden, Melissa L.; Darensbourg, Marcetta Y. (award winner best oral presentation). “Development of Metal Dithiolate Complexes as Bidentate Ligands for Organometallic Chemistry: Inspired by Acetyl coA Synthase.” (award winner best oral presentation)
Chemistry and Biology Interface Conference, August 21, 2004, Texas A & M University, College Station, TX. Rampersad, M. V.*; Jeffery, Stephen P.; Golden, Melissa L.; Darensbourg, Marcetta Y. “Development of Metal Dithiolate Complexes as Bidentate Ligands for Organometallic Chemistry: Inspired by Acetyl coA Synthase.” (oral presentation)
36th International Conference on Coordination Chemistry, July 18-23, 2004, Mérida, Yucatán, México. Rampersad, M. V.*; Jeffery, Stephen P.; Golden, Melissa L.; Darensbourg, Marcetta Y. “Development of Metal Dithiolate Complexes as Bidentate Ligands for Organometallic Chemistry.” (poster presentation)
225th American Chemical Society Meeting, March 25, 2004, New Orleans, LA. Rampersad, M. V.*; Darensbourg, Marcetta Y.; Miller, Matthew L. “Synthesis and Structural Characterization of Heteronuclear Clusters Comprised of Nickel and Copper Bridged by Thiolates.” (poster presentation)
Pacifichem 2000 Conference, December 14, 2000, Honolulu, Hawaii. Rampersad, M. V.*; Howell, Roberta.; Francesconi, Lynn. C. “Contrasting Reactive Properties of Rhenium and Technetium with Cyclic Metaphosphates and the Phosphate Based Polyoxotungstate [ P2W17O61]-10.” (award winner best poster presentation)