The review article ” Helicobacter pylori and its Effects on Human Health and Disease” (2011), Kamanger, Sheikahattari, and Mohebtash showed how H. pylori been discovered by Marshall and Warren, as well as how H. pylori could influence human health. Kamanger et al provided information of how marshall proved H. pylori that could lead to gastric cancer; he drank H. pylori from Petri dish and symptoms of gastric appeared afterward, the science district did not expect the results and the discovery were proven still. The purpose of this article was to discuss how H. pylori could cause or prevent the formation of diseases in order to improve our understanding on prevention and, causation of some diseases. This article has potential to provide information on treatments design.