Rhetorical precis:
(1) LydiaE. Wroblewski, a member of the Division of Gastroenterology and Department of Medicine in Nashville, Tennessee, wrote of her work entitled “Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk” which explains how H. pylori is tightly correlated to the formation of gastric cancers in infected individuals, and how specific virulence factors including CagA and VacA toxins produced by the bacteria contribute to cancer formation. (2) Wroblewski’s study provides corroboration that virulence factors produced by H. pylori, along with the bacterium’s anatomy and physiology, alter the host gut environment, and over time alter the gut endothelial cell genes to produce cancerous endothelial cells. (3) The purpose of Wroblewski’s work is to better understand the mechanism by which certain H. pylori strains contribute to cancer in order to better prevent gastric endothelial cancer formation since a large portion of the world’s population is infected with the bacteria. (4) Wroblewski’s use of scientific jargon and reliance on the audience’s understanding of biological molecular processes infers an intended audience of microbiological researchers and biologists interested in microbial virulence and potential therapeutic treatment options for H. pylori infected individuals.
Lydia E. Wroblewski, Richard M. Peek Jr., Keith T. Wilson. 2010. Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk. 23(4): 713-739.
