Outline Lecture #31 Spring 2017

Lipid Metabolism

Catabolism of lipids

  • Release of fatty acids from fats – HERE
  • Phospholipase sites of action – HERE
  • Hormonal control of fat breakdown – HERE
  • Formation of acyl-CoA – HERE
  • Role of carnitine in acyl transport – HERE
  • Beta oxidation of fatty acids – HERE
  • Breakdown of stearic acid – HERE
  • Catabolism of odd-carbon fatty acids
  • Catabolism of unsaturated fatty acids
    • HERE
    • Polyunsaturated fatty acid oxidation – HERE
  • Ketone body metabolism – HERE

Fatty Acid Biosynthesis

  • Movement of acetyl groups to cytoplasm – HERE
  • Formation of malonyl-CoA – HERE
  • Acetyl–CoA carboxylase reaction –HERE
  • Synthesis of palmitic acid – HERE
  • Coenzyme A / ACP similarity – HERE
  • Cellular division of labor

Other Lipids

  • Synthesis of triacylglycerols – HERE
  • Synthesis of phosphatidylethanolamine – HERE / HERE / HERE
  • Synthesis of sphingolipids – HERE
  • Cholesterol biosynthesis – HERE / HERE / HERE / HERE / HERE
  • Statins – HERE
  • Synthesis of bile acids – HERE
  • Synthesis of steroid hormones – HERE

Lipoprotein Complexes – HERE

Movement of lipids in body HERE

Fate of cholesterol in cell – HERE

Atherosclerosis

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