Outline Lecture #17 Spring 2017

Transcription

Overview

  • General Features – TABLE
  • Prokaryotes
    • RNA Polymerase
    • Sequences in Promoters – HERE
    • Chain of Events – HERE (Initiation / Termination / Elongation)
    • Chain Termination
      • Factor Independent – HERE
      • Factor Dependent – HERE
    • Regulation
      • Sigma Factors
      • Transcription Factors
      • Promoter Sequence Elements – HERE
      • Operons
        • Lac Operon
          • Structure – HERE
          • Repression – HERE
          • Catabolite Repression – HERE
        • Trp Operon
          • Structure – HERE
          • Attentuation – HERE
  • Eukaryotes
    • 3 Polymerases
    • Pol II Subunits – TABLE
    • Pol II Promoters – HERE
      • Initiation Factors – TABLE
        • Process – HERE
        • TBP bending of DNA
    • Transcription Regulation
      • Enhancers – HERE
        • Response Elements – TABLE

DNA Binding Proteins

  • Binding Domains (Motifs)
    • Helix-turn-helix – HERE
    • Zinc-Fingers – HERE / HERE
    • Leucine Zipper – HERE

Post-Transcriptional Modification of RNA

  • tRNA
  • mRNA
    • Caps in Eukaryotes – HERE
    • Polyadenylation
  • Split Genes and Splicing in Eukaryotes – HERE / HERE
  • Ribozymes and Self-Splicing
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