Zif268

Zif268, also known as Egr1(Early Growth Response Protein 1) is a transcription factor. It can be found in the nucleus of the cell where it regulates transcription of genes required for cell differentiation and mitogenesis. Zif268 is composed of 543 amino acids with a molecular weight of 57.5 kDa. Its structure consists of three zinc fingers.

I plan to sculpt hands out of clay as the base/stand to hold the protein. And then I will replace some of the fingers of the hands with the ‘zinc finger’ structures with a stretch of DNA running through the center of the structure. I plan to make the protein and DNA out of wire. Does anyone have any suggestions on sturdy wire that is easy to bend?

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