Xiaoxi Dong


B.A. Fudan University, Shanghai, China

PhD. Institute of Biophysics, Chinese Academy of science, Beijing, China


Research interests:

Interaction between commensal/pathogenetic microbes and their host

Functional/phylogenetic profiling of microbial community from metagenomic/16s rRNA sequencing data

Host functional analysis based on gene expression, metabolomics and other high-throughput omics data.

inference relationship between microbe-host using statistical modeling and network analysis based on omics dataset from host and their microbiome.



A Morgun, A Dzutsev, X Dong, RL Greer, DJ Sexton, J Ravel, M Schuster, et al. “Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks.” Gut(2015): gutjnl-2014.

X Dong, A Yambartsev, SA Ramsey, LD Thomas, N Shulzhenko, et al. “Reverse enGENEering of Regulatory Networks from Big Data: A Roadmap for Biologists.” Bioinformatics and biology insights9 (2015): 61.

L Deng*, X Dong*, A Wu, T Song, T Jiang. “Coevolution signals capture the specific packing of secondary structures in protein architecture.” Protein & cell5.6 (2014): 480-483. (* co-first author)

Y Wang, X Zhang, H Zhang, Y Lu, H Huang, X Dong, J Chen, J Dong, et al. “Coiled-coil networking shapes cell molecular machinery.”Molecular biology of the cell23.19 (2012): 3911-3922.

Y Hu*, X Dong*, A Wu, Y Cao, L Tian, T Jiang. “Incorporation of local structural preference potential improves fold recognition.” PloS one6.2 (2011): e17215-e17215.  (* co-first author)

L Tian, A Wu, Y Cao, X Dong, Y Hu, T Jiang. “NCACO-score: An effective main-chain dependent scoring function for structure modeling.” BMC bioinformatics12.1 (2011): 208.

H Zhang, J Chen, Y Wang, L Peng, X Dong, Y Lu, AE Keating, T Jiang. “A computationally guided protein-interaction screen uncovers coiled-coil interactions involved in vesicular trafficking.” Journal of molecular biology392.1 (2009): 228-241.

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